5. Adrenomimetics.

1. The patient of 40 years suffered from bronchial asthma for 10 years. Acompanying this disease is cardiac arrhythmia (tachycardia). Specify the drug which may be used for elimina­tion of bronchospasm with keeping into account the acompanying disease?

A. * Salbutamolum

B. Orciprenaline

C. Eohedrine

D. Adrenaline

E. Isadrinum

2. Expressed arterial hypotension had developed in the patient during an operation which had been carried out under phthorotanum-general anesthesia. Which- from the listed medicines below should be introduced to the patient to normalize he's arterial blood pressure?

A. *Mesatonum

B. Strophanthin

C. Ephedrine hydrochloride

D. Noradrenatlnum hydrotartrate

E. Adrenaline

3. Indicate mechanism of broncho-lytic action of salbutamol?

A. *Stimulation of beta-2-adrenoceptors

B. Inhibition of phosphodiesterase

C. Activation of noradrenaline synthesis

D. Blockade of H-f-histamine receptors

E. Blockade of M-cholinoceptors

4. A 40 year old patient has been suffering from bronchial asthma for 10 years accompanied with cardiac arrthymia (tachycardia). Indicate adrenomimetic agent which should be administered for elimination of bronchospasm taking into account accompanied heart disease.

A. *Salbutamolum

B. Adrenaline

C. Isadrinum

D. Orciprenalinum

E. Ephedrinum

5. Salbutamol was administered to a 30 year old woman due to danger of having miscarriage as it causes decrease of contractile ability of myometrium. Indicate mechanism of sympathomimetics.

relaxing action upon the uterus of this drug.

A. *Stimulation of beta-2-adrenoceptors

B. Stimulation of aipha-2-adrenoceptors

C. blockade of beta- f- adrenoceptors

D. Inhibition of monoaminooxydase

E. Blockade of phosphodiesterase

6. A female patient was admitted to a hospital with complaints of unpleasant sensations in the heart area, attacks of acute weakness, sometimes loss of consciousness. Examination of patient revealed atrioventricular blockade. Indicate the group of drugs that should be appointed in this situation.n

A. *beta-adrenomimetics (Isadrinum)

B. Cardiac glycosides (Digitoxin)

C. beta-adrenoblockers (Anapritinum)

D. Calcium channel blockers (Verapamil)

E. Sympatholytics (Ornidum)

7. Anaphylactic shock has developed in a patient after novocainum (procaine) injection. What agent supresses histamine release from mast ceils and eliminates main symptoms of anaphylactic shock?

A. Beclometasone

B. Euphillinum (aminophilline)

C. *Adrenaline

D. Ketotifen

E. Cromolin natrium (cromoglycic acid)

8. A doctor diagnosed hypoglyce­mic coma in a patient with diabetes mellitus and administered glucose solution IV to him. Patient's condition improved. What drug can be used additionally as the biochemical antago­nist of insulin?

A. *Adrenaline

B. Mesatonum (phenylephrine)

C. Dobutamine

D. Isadrinum (isoprenaline)

E. Dopamine

9. A patient with chronic bronchi­tis has been taking ephedrine for a long time. What is the mechanism of the drug action?

A. *Stimulation of noradrenaline release into synaptic cleft

B. Blockade of noradrenaline release into synaptic cleft

C. Stimulation of a-adrenoceptors

D. Blokade of b-adrenoceptors

E. Direct influence on smooth muscles of bronchi

10. Indicate the state which requires introduction of ephedrine?

A. *Arterial hypotension

B. Caffeine poisoning

C. Tachycardia

D. Arterial hypertension

E. insomnia

11. A patient with obstructive bronchitis has been taking ephedrine for a long time without doctor's control. What side effect can be observed in the patient?

A. *Excitation of CNS

B. Hypotension

C. Bradycardia

D. Apathy

E. Sleepiness

12. What drug can be used for treatment of hypotension due to peripheral vascular insufficiency?

A. *alfa-adrenomimetic

B. b-adrenomimetic

C. Analeptic

D. Colloidal plasma substitute

E. Salt plasma substitute

13. Mesatonum (phenylephrine) was introduced to a patient with collapse for correction of blood pressure. What is the mechanism of action of the drug?

A. *Stimulation of alfa-adrenoceptors

B. Blockade of alfa-adrenoceptors

C. Blockade of beta-adrenoceptors

D. Stimulation of α-β adrenoceptors

E. Stimulation of b-adrenoceptors

14. Collapse developed in a patient due to decrease of peripheral vessels tone. What preparation is the most efficient in this situation?

A. *Mesatonum (phenylephrine)

B. Proserinum (neostigmine)

C. Isadrinum (isoprenaline)

D. Clophelinum (clonidine)

E. Prazosine

15. What drugs should be used for bronchospasm treatment?

A. *beta2-adrenomimetics

B. Sympatolytics

C. alfa-adrenomimetics

D. Cholines terase inhibitors

E. M-cholinomimetics

16. Salbupart (salbutamol) was introduced to a 30-years-old pregnant woman with threatened abortion. It reduced contractile activity of myometrium. Indicate the mechanism of action of salbutamol?

A. *Stimulation of beta2-adrenoceptors

B. Blockade of beta f-adrenoceptors

C. Stimulation of alfa2-adrenoceptors

D. Inhibition of monoaminooxidase

E. Inhibition of phosphodiesterase

17. Indicate broncholytic drug from the group of selective beta2-adrenomimetics.

A. *Salbutamol

B. Methacinum

C. Isadrinum (isoprenaline)

D. Euphillinum (aminophilline)

E. Atropine

18. An attack of bronchial asthma developed in 40-years-old woman. Indicate the drug belonging to beta2-adrenomimetics which is effective for elimination of the attack

A. *Fenoterol

B. Ephedrine

C. Adrenaline

D. Plathvphiiline

E. Atropine

19. A 40-years-old patient has been suffering from bronchial asthma for 10 years, fie has also an accompa­nying disease cardiac arrhythmia (tachycardia). What adrenomimetic can be administered for elimination of bronchospasm?

A. *Salbutamol

B. Adrenaline

C. Isadrinum (isoprenaline)

D. Atropine

E. Ephedrine

20. A patient with bronchial asthma has been taking isadrinum (isoprenaline) inhalation for a long time. He notices the drug leads to tachycardia and headache. Which agent from listed below can be used instead of isadrinum?

A. *Salbutamol

B. Mesatonum (phenylephrine)

C. Anapriiinum (propranolol)

D. Dobutaminum

E. Cordiaminum (nikethamide)

21. A patient with bronchial asthma did not tell doctor that he had attacks of stenocardia sometimes. The doctor administered to him the drugs. After a patient started to take this drug, attacks of bronchial asthma became rare but attacks of stenocar­dia became more frequent. Indicate the drug which was administered by the doctor?

A. *Isadinum (isoprenaline)

B. Salbutamol

C. Euphillinum (aminophilline)

D. Cromolin natrium (cromoglycic acid)

E. Fenoterolum

22. A patient with bronchial asthma had been taking tablets which caused insomnia, headache, increased blood pressure. What medicine can cause such complications?

A. *Ephedrine

B. Isadrinum

C. Cromolin sodium

D. Euphyline

E. Oxprenololum