1. Vaccines

2. Immune sera

3. Toxoids

4. Antibiotics

5. Vitamins

*2013* a child cut his leg with a piece of glass while playing and was brought to the clinic for the injection of tetanus antitoxin. In order to prevent the development of anaphylactic shock the serum was administered by Bezredka’s method. What mechanism underlies this method for desentization of the body?

1. Binding of IgE fixed to the mast cell

2. Stimulation of the synthesis of antigen-specific IgG

3. Blocking the mediator synthesis in the mast cell

4. Stimulation of the immune tolerance to the antigen

5. Binding of IgE receptors to the mast cell

Vaccines and immune sera

“06” “08” One of the medicines for wide usage is obtained by inactivation of bacterial exotoxin with phormaldehide. Which purpose does it use for?

1. *For active immunization

2. For immunocorrection

3. For treatment of toxemia

4. For passive immunization

5. For serodiagnostics

“07” Bacterial preparations are subdivided into groups according to their purpose and production principles. What group do the preparation for initiation of active immunity relate to?

1. Bacteriophages

2. Immune sera

3. Immunoglobulins

4. *Vaccines

5. Monoclonal antibodies

LB/ A factory of biological medicines some types of vaccines are produced. Which from the list belongs to group of obligate usage?

1. Anti measles vaccine

2. Anti rabies vaccine

3. Plague vaccine

4. Anti enteric fever

5. Anti influenza vaccine

“06” According to schedule of vaccination specific prophylaxis of measles are made for children at age of 1 year. Which type of vaccine is used for this?

1. Gene-engineering

2. *Alive

3. Chemical

4. Toxoid

5. Inactivated

LB/ Low level of immune status is contraindications for vaccination against poliomyelitis due to development of paralytic form of poliomyelitis. What type of medicine may cause such form of infection?

1. Sabin vaccine

2. Solk vaccine

3. DPT vaccine

4. BCG vaccine

5. TABte vaccine

“04” Associated vaccine DPT is used for prevention of child infections. Indicate the type of vaccine against whooping cough that is a part of this vaccine.

1. Toxoid

2. *Inactivated

3. Gene-engineeering

4. Chemical

5. Attenuated

LB/ during production of vaccine for enteric fever prevention bacteria of virulent strain were cultivated on the optimal nutrient medium. Then cells were separated from culture fluid by centrifugation and treated with formaldehyde. Which type does this vaccine belong to?

1. Inactivated

2. Attenuated

3. Chemical

4. Toxoid

5. Autovaccine

B-2 To produce antitetanus gamma-globulin hyperimmunization of donors with tetanus toxoid is made. Which class of immunoglobulins is prevalent in this medicine?

1. Ig G

2. IgA

3. IgM

4. IgD

5. IgE

B-2 For specific prophylaxis of diphtheria, tetanus and whooping cough vaccine DPT is used that contains microorganisms and inactivated with formaldehyde exotoxins. What type of vaccine does it belong to?

1. Associated

2. Gene-engineering

3. Toxoides

4. Chemical

5. Alive

B-2 Genes of hepatitis B virus that are responsible for HBsAg synthesis were integrated with yeast cell genome. This cell was used in production of prophylactic medicine for prevention of this disease. What is this?