Tests for verification of initial level of knowledges

1. Syphilis is caused by:

1. Blue-pus bacillus;

2. Streptococcus;

3. Staphylococcus;

4. Escherichia coli;

5. Treponema pallidum.

2. The basic signs of syphilis are:

1. Chancroid;

2. Hard chancre;

3. Polyadenitis;

4. Regional scleradenitis;

5. Negative serum reactions;

6. Positive serum reactions;

7. Syphilids.

3. The most reliable method of diagnostics of tertiary syphilis is:

1. Examination of material taken from the bottom of ulcer;

2. Examination of neurolymph;

3. Blood examination (Wassermann's reaction);

4. T. pallidum immobilization test;

5. Precipitin reactions.

4. The most specific serological reaction for syphilis is:

1. The fluorescence test;

2. T. pallidum immobilization test;

3. Wassermann's reaction with the treponemal antigen;

4. Wassermann's reaction with the cardiolipin antigen;

5. Microreaction.

5. Who must be inspected (serological test of blood) in case of suspicion of congenial syphilis?

1. Father;

2. Mother;

3. Child;

4. Brothers and sisters of child;

5. Mother’s relatives;

6. Father’s relatives.

6. Select multiplicity and terms of examination of pregnant for syphilis (Wassermann's reaction):

1. Examination is carried out not less than twice, during the first and second periods of pregnancy;

2. In each 2 monthes;

3. Single examination before childbirth;

4. Single examination in the II trimester of pregnancy.

7. A 22 years old woman complains of appearance of ulcer on a large vulvar lips. The subjective feelings are absent. In anamnesis – there was a sexual contact with a little known man month ago. What examinations must be done first of all for determination of diagnosis?

1. Examination for T. pallidum;

2. Examination for gonococci;

3. Examination for trichomonads;

4. Examination for fungi;

5. Examination for Chlamydia.

8. The serological reactions of pregnant in the first and second half of pregnancy is conducted in:

1. Skin and venereal dispensary;

2. Maternity ward;

3. Gynaecological department;

4. Maternity welfare centre;

5. Out-patients' clinic.

9. After contact with a syphilitic patient Wassermann's reaction becomes positive in:

1. 1 week;

2. 2 weeks;

3. 4-5 weeks;

4. 6-8 weeks;

5. 9-10 weeks.

10. After appearance the hard chancre Wassermann's reaction becomes positive in:

1. 1 week;

2. 2 weeks;

3. 3-4 weeks;

4. 5-6 weeks;

5. 8-9 weeks.

11. What serological reactions for syphilis can be positive in the case of the primary seronegative period of syphilis?

1. IFT;

2. Wassermann's reaction;

3. IFT, TPI;

4. TPI;

5. Classical, serological reactions.

12. What method of diagnosing is used in everyday practice for the reveal of T. pallidum?

1. Cultivation on nutrient mediums;

2. Staining by the Romanovsky-Giemsa;

3. Staining by methylene blue;

4. Examination of native preparations in dark field illumination of the microscope;

5. Silvering by the Morozov.

13. After an infection with syphilis, usually, the Wassermann's reaction becomes positive in:

1. 3-4 weeks;

2. 6-8 weeks;

3. 9-12 weeks;

4. 3-4 months;

5. 2-4 years.

14. What physiological secretion and excreta can be contagious in syphilis?

1. Saliva;

2. Sweat;

3. Urine;

4. Milk;

5. Sperm.

15. What serological reactions for syphilis can be positive in the case of the primary seropositive period of syphilis?

1. Express-method;

2. IFT;

3. Wassermann's reaction;

4. TPI;

5. Classical, serological reactions.

16. What serological reactions can be positive in the case of secondary recurrent syphilis?

1. Express-method;

2. IFT;

3. Wassermann's reaction;

4. TPI;

5. IFT, TPI.

17. The positive results of the followings tests are needed for diagnosis of primary seropositive period of syphilis with typical clinical picture:

1. IFT;

2. TPI;

3. Microreaction;

4. Wassermann's reaction.

18. What serological reactions will be positive in the case of secondary early syphilis?

1. Express-method;

2. IFT;

3. Wassermann's reaction;

4. IFT, TPI;

5. All of reactions are negative.

19. The diagnosis of syphilis always is based on signs:

1. Clinical manifestation;

2. Information of anamnesis;

3. Laboratory examinations;

4. All above-listed.

20. The laboratory methods of diagnostics of syphilis are distinguished:

1. Detection of causative agent of disease in lesions;

2. Serological reactions for syphilis;

3. Microprecipitation test;

4. Immunofluorescence test;

5. T. pallidum immobilization test;

6. All above-listed.

21. The T. pallidum immobilization test is used with a purpose for:

1. Making the diagnosis of primary syphilis;

2. Making the diagnosis of early syphilis;

3. Making the diagnosis of latent syphilis;

4. Appraising the efficacy of antisyphilitic therapy;

5. Taking off the record completely cured patient.

22. What reaction is used for express-diagnostics of syphilis?

1. RW;

2. Microprecipitation test;

3. IFT;

4. TPI.

23. Criteria of cure of syphilis is considered:

1. Quality of the conducted treatment;

2. Data of clinical inspection (skin, mucous membranes, internal organs, nervous system, organs of sense);

3. Data of laboratory examinations (CSR, IFT, TPI);

4. All above-listed.

24. Wassermann's reaction is based on:

1. Hematolysis;

2. Yellow-green fluorescence of T. pallidum;

3. Recognition of false positive non-specific results of standard serum reactions.

25. The basic specific antisyphilitic medicines are considered all from following, except for:

1. Penicillin;

2. Bicillin;

3. Retarpen;

4. Extencilline;

5. Tetracycline.

26. Nonspecific medicines for treatment of syphilis are considered:

1. Immune preparations (Thymogen, Thymalin, Laferon, Methyluracil);

2. The group of stimulating preparations (Pyrorenal, Aloe, FIBS, Plasmol, extract of placenta and others like that);

3. Vitamin therapy;

4. The group of reserve.

27. What can be taken excretions for laboratory examination from?

1. Lesions;

2. Aspirate of a regional lymph node;

3. Serum;

4. Neurolymph;

5. Scales from papular shyphilids.

28. Criteria of cure of syphilis are:

1. Patients who have completed antisyphilitic treatment are kept under dispensary care;

2. The patient visits the physician once in three months during the first two years;

3. The patient visits the physician once in six months during the third year for medical examination and serological tests and then they are taken off the record;

4. During 3 years;

5. During 5 years.

29. Basic medicines for treatment of patients with syphilis are:

1. Preparations of penicillin;

2. Preparations of tetracycline;

3. Preparations of erythromycin;

4. Macrolids.

30. What is characteristic for latent early syphilis with sharply positive Wassermann's reaction:

1. Low titre of reaginic antibodies;

2. High titre of reaginic antibodies;

3. The titre of reaginic antibodies does not have any value.

31. Such complications can be during the treatment of syphilis with penicillin except for:

1. Anaphylactic shock;

2. Toxicodermia;

3. Hives;

4. Candidiasis;

5. Alopecia.

32. The second recurrent syphilis is suspected in a patient. CSR are weakly positive. It is necessary to apply the followings reactions:

1. Kolmer's test;

2. The fluorescence test;

3. T. pallidum immobilization test;

4. Microreaction;

5. Wassermann's reaction with the cardiolipin antigen.

33. Patients with a gonorrhoea with the unrevealed source of infection, but having a permanent address and work:

1. Preventive antisyphilitic treatment is conducted;

2. Preventive antisyphilitic treatment is not conducted;

3. Clinical and serological control is carried out during 3 months;

4. Clinical and serological control is carried out during 6 months;

5. Right 2) and 3).

Literature.

The basic:

1. Lecture on the theme.

2. Guideline for self-study of students by preparation for practical lesson 22.

3. Yu. K.Skripkin and M.V. Milich. Skin and Venereal Diseases, English translation, Mir Publishers, 1981, p.496-508.

The additional:

1. Fitzpatrick et al. Dermatology in General Medicine, 4th ed. New York, McGraw-Hill, 1993.

2. Fitzpatrick. Color Atlas and Synopsis of Clinical Dermatology, 3rd Edition, 1997.

3. P.N Behl, A. Aggarwal, Govind Srivastava. Practice of Dermatology, 9th Edition, 2002, p. 50-51, 242-243.