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Biomedical engineering

2

•Systems Physiology

•Bionanotechnology

•Neural Engineering

Sometimes, disciplines within BME are classified by their association(s) with other, more established engineering fields, which can include:

•Chemical engineering - often associated with biochemical, cellular, molecular and tissue engineering, biomaterials, and biotransport.

•Electrical engineering - often associated with bioelectrical and neural engineering, bioinstrumentation, biomedical imaging, and medical devices. This also tends to encompass Optics and Optical engineering - biomedical optics, imaging and related medical devices.

•Mechanical engineering - often associated with biomechanics, biotransport, medical devices, and modeling of biological systems, like soft tissue mechanics.

Roles of a Biomedical Engineer in a Hospital

•Advise and assist in the application of instrumentation in clinical environments.

•Provide leadership, guidance, support and supervision to the section staff and take responsibility in the day to day operation of the clinics.

•Evaluate the safety, efficiency, and effectiveness of biomedical equipment.

•Ensure that all medical equipment is properly maintained and documented.

•Provide engineering and technical expertise on all matters related to medical technology, especially in the process of planning, review, evaluation, and specification of medical equipment.

•Install, adjust, maintain, and/or repair biomedical equipment. Evaluate, negotiate and manage service contracts.

•Adapt or design computer hardware or software for medical science uses.

•Develop and provide a comprehensive in-service education program on the safe and effective use of medical equipment for both medical and nursing staff.

•Advise hospital administrators on the planning, acquisition, and use of medical equipment.

•Develop and implement short and long term strategies for the development and direction of the department to effectively manage medical equipment and technology in the clinics.

•Minimize, investigate and rectify hazard risks associated with medical equipment use.

•Perform other duties within the scope of the job and its technical capacity and expertise.

Bionics and Biomedical Engineer

Artificial body part replacement is just one of the things that bionics can do. Concerned with the intricate and thorough study of the properties and function of human body systems, bionics may be applied to solve some engineering problems. Careful study of the different function and processes of the eyes, ears, and other organs paved the way for improved cameras, television, radio transmitters and receivers, and many other useful tools. These developments have indeed made our lives better, but the best contribution that bionics has made is in the field of biomedical engineering. Biomedical Engineering is the building of useful replacements for various parts of the human body. Modern hospitals now have available spare parts to replace a part of the body that is badly damaged by injury or disease. Biomedical engineers who work hand in hand with doctors build these artificial body parts.

Biotechnology (see also relatedly bioengineering) can be a somewhat ambiguous term, sometimes loosely used interchangeably with BME in general; however, it more typically denotes specific products which use "biological systems, living organisms, or derivatives thereof." [2] Even some complex "medical devices" (see below) can reasonably be deemed "biotechnology" depending on the degree to which such elements are central to their principle of operation. Biologics/Biopharmaceuticals (e.g., vaccines, stored blood product), genetic engineering, and various agricultural applications are some major classes of biotechnology.

Micromass cultures of C3H-10T1/2 cells at varied oxygen tensions stained with Alcian blue.

Biomedical engineering

3

Pharmaceuticals are related to biotechnology in two indirect ways: 1) certain major types (e.g. biologics) fall under both categories, and 2) together they essentially comprise the "non-medical-device" set of BME applications. (The "Device - Bio/Chemical" spectrum is an imperfect dichotomy, but one regulators often use, at least as a starting point.)

Tissue engineering

Tissue engineering is a major segment of Biotechnology.

One of the goals of tissue engineering is to create artificial organs (via biological material) for patients that need organ transplants. Biomedical engineers are currently researching methods of creating such organs. Researchers have grown solid jawbones[3] and tracheas from human stem cells towards this end. Several artificial urinary bladders actually have been grown in laboratories and transplanted successfully into human patients.[4] Bioartificial organs, which use both synthetic and biological components, are also a focus area in research, such as with hepatic assist devices that use liver cells within an artificial bioreactor construct.[5]

Genetic engineering

Genetic engineering, recombinant DNA technology, genetic modification/manipulation (GM) and gene splicing are terms that apply to the direct manipulation of an organism's genes. Genetic engineering is different from traditional breeding, where the organism's genes are manipulated indirectly. Genetic engineering uses the techniques of molecular cloning and transformation to alter the structure and characteristics of

genes directly. Genetic engineering techniques have found success in numerous applications. Some examples are in improving crop technology (not a medical application per se; see BioSystems Engineering), the manufacture of synthetic human insulin through the use of modified bacteria, the manufacture of erythropoietin in hamster ovary cells, and the production of new types of experimental mice such as the oncomouse (cancer mouse) for research.

Neural engineering

Neural engineering (also known as Neuroengineering) is a discipline that uses engineering techniques to understand, repair, replace, or enhance neural systems. Neural engineers are uniquely qualified to solve design problems at the interface of living neural tissue and non-living constructs.

Pharmaceutical engineering

Pharmaceutical Engineering is sometimes regarded as a branch of biomedical engineering, and sometimes a branch of chemical engineering; in practice, it is very much a hybrid sub-discipline (as many BME fields are). Aside from those pharmaceutical products directly incorporating biological agents or materials, even developing chemical drugs is considered to require substantial BME knowledge due to the physiological interactions inherent to such products' usage. With the increasing prevalence of "combination products," the lines are now blurring among healthcare products such as drugs, biologics, and various types of devices.

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