Italian political situation remains uncertain

because the Italian Government in the House of Representatives already does not have a majority, Berlusconi on the 8th night stand, he would in Parliament both houses to pass a bill to stabilize the domestic financial position after the resignation.

rumors or misunderstanding in order to avoid increased market volatility, 9 Italian President Giorgio Napolitano issued a statement, stressed that Berlusconi’s resignation there is no uncertainty. He said that the current Italian political parties have agreed to financial stability bill will be “few days” get through both houses of Congress.

According to Italian news agency ANSA, the Italian Senate and House have decided this week by the Stabilization Act, which means that Berlusconi’s government much time, but still on the major political parties in Italy formation of the transitional government or early elections debated.

analysts pointed out that the EU and other countries in the euro area, they are not concerned with the topic of the next prime minister of Italy, but Italy must quickly form a government that gets quickly to fulfill commitment to reform, effectively control the scale of debt and restore market confidence.

Cirrhosis

Cirrhosis  is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules (lumps that occur as a result of a process in which damaged tissue is regenerated), leading to loss of liver function. Cirrhosis is most commonly caused by alcoholism, hepatitis B and C, and fatty liver disease, but has many other possible causes. Some cases are idiopathic, i.e., of unknown cause.

Ascites (fluid retention in the abdominal cavity) is the most common complication of cirrhosis, and is associated with a poor quality of life, increased risk of infection, and a poor long-term outcome. Other potentially life-threatening complications are hepatic encephalopathy (confusion and coma) and bleeding from esophageal varices. Cirrhosis is generally irreversible, and treatment usually focuses on preventing progression and complications. In advanced stages of cirrhosis the only option is a liver transplant.

Cirrhosis leading to hepatocellular carcinoma (autopsy specimen).

Macroscopically, the liver is initially enlarged, but with progression of the disease, it becomes smaller. Its surface is irregular, the consistency is firm and the color is often yellow (if associates steatosis). Depending on the size of the nodules there are three macroscopic types: micronodular, macronodular and mixed cirrhosis. In micronodular form (Laennec's cirrhosis or portal cirrhosis) regenerating nodules are under 3 mm. In macronodular cirrhosis (post-necrotic cirrhosis), the nodules are larger than 3 mm. The mixed cirrhosis consists in a variety of nodules with different sizes.

However, cirrhosis is defined by its pathological features on microscopy: the presence of regenerating nodules of hepatocytes and the presence of fibrosis, or the deposition of connective tissue between these nodules. The pattern of fibrosis seen can depend upon the underlying insult that led to cirrhosis; fibrosis can also proliferate even if the underlying process that caused it has resolved or ceased. The fibrosis in cirrhosis can lead to destruction of other normal tissues in the liver: including the sinusoids, the space of Disse, and other vascular structures, which leads to altered resistance to blood flow in the liver and portal hypertension.

As cirrhosis can be caused by many different entities which injure the liver in different ways, different cause-specific patterns of cirrhosis, and other cause-specific abnormalities can be seen in cirrhosis. For example, in chronic hepatitis B, there is infiltration of the liver parenchyma with lymphocytes;  in cardiac cirrhosis there are erythrocytes and a greater amount of fibrosis in the tissue surrounding the hepatic veins; in primary biliary cirrhosis, there is fibrosis around the bile duct, the presence of granulomas and pooling of bile;  and in alcoholic cirrhosis, there is infiltration of the liver with neutrophils.