- •Process of metabolism within a cell 1 59
- •In cellular metabolism, energy-requiring reactions occur because they are coupled with reactions that cleave [kliːv] atp.
- •164 Chapter 6 cellular metabolism
- •Metabolic pathways 165
- •In the Krebs cycle, intermediary metabolites, such
- •In the Embden-Meyerhof pathway of glycolysis, glucose is partially broken down into pyruvate, two nadh molecules are formed, and the energy released leads to a net yield of two atp.
- •Intestinal Yeast Infections Cause Intoxication
- •174 Chapter 6 cellular metabolism
- •Production of Cheese
- •In photosynthesis, light energy is captured and used
- •Metabolic pathways 179
- •180 Chapter 6 cellular metabolism
- •182 Chapter 6 cellular metabolism
- •Explosions that Destroy Houses Traced to Methane from Landfill
- •188 Chapter 6 cellular metabolism
Methane
is produced at sites where organic matter landfills have been blown
off their foundations be-
decomposes
and creates anaerobic conditions. Sani- cause methane from a nearby
landfill seeped through
tary
landfills represent such sites, and methane pro- the ground into
their basements. The methane was
duction
at landfills is so extensive that it may be ignited by the pilot
lights of the water heater or fur-
trapped
and used as a fuel. In some cases, however, nace systems. The
explosions moved the houses sev-
such
methane production represents a serious prob- eral feet away from
their original locations. These in-
lem,
particularly for nearby houses. Several houses in cidents serve as
important reminders to keep houses
Kentucky
and other states that were located near a safe distance from
landfills.
The
production of methane by methanogens has several practical
consequences. Methane is found in natural gas. It is a flammable
gas. Methane seeping from landfills, where it is produced by
methanogens degrading the waste deposits, sometimes enters nearby
houses and causes explosions. Some sewage treatment facilities
collect the methane that is formed
during
anaerobic decomposition of wastes and use it as a source of fuel for
generating heat and electricity. Some communities are supplied
with a portion of their natural gas (methane) from this metabolic
process. In the future, methane produced by microorganisms may
be used as a fuel for automobiles.
SUMMARY
Process
of Metabolism Within a Cell (pp. 158-164)
Cells
exhibit various strategies for converting chemical and light
energy into the energy stored within ATP, the central currency of
energy of the cell. These processes of cellular metabolism also
transform starting materials into the organic chemicals that
make up the cell's structural and functional components.
Role
of Enzymes (pp. 158-159)
Enzymes
are proteins that act as biological catalysts to accelerate the
rates of chemical reactions by lowering the activation energy
necessary for the reaction to occur. Different enzymes are needed
to catalyze different reactions, each cell having thousands of
enzymes, each enzyme binding only specific substrates to its
active site.
Coenzymes
and Oxidation-reduction
Reactions
(pp. 159-160)
An
oxidation-reduction or redox reaction involves the transfer of an
electron from a donor, which is oxidized, to an acceptor,
which is reduced. All redox reactions must be balanced.
Cellular metabolism generates reducing power to convert
substrate materials into the more reduced molecules of the cell by
coupling oxidation reactions with the reduction of coenzymes.
ATP
and Cellular Energy (pp. 160-161)
All
cells carry out metabolic reactions that transfer energy to ATP.
ATP requires energy-releasing metabolic reactions for its
formation. ATP's stored energy is used to drive energy-requiring
biosynthetic reactions. Breaking an ATP high-energy bond
yields 7300
calories
per mole of energy. Substrate level phosphorylation is the
generation of ATP from ADP + Pj coupled to energetically
favorable reactions. The formation of ATP can also be driven by
a protonmotive force in chemiosmosis.
Metabolic
Pathways and Carbon Flow (pp. 161-162)
The
metabolic pathways utilized in ATP generation involve various
intermediary metabolites linked together in a series of small
steps to form unified biochemical pathways. In a catabolic
pathway, larger molecules are split into smaller ones. Cells form
relatively small molecules that can act as the basis for the
carbon skeletons of larger macromolecules that are synthesized in
anabolic (biosynthetic) pathways.
Autotrophic
and Heterotrophic
Metabolism
(pp. 162-164)
The
synthesis of ATP can be achieved autotrophi- cally—through the
oxidation of inorganic substrates or through the conversion of
light energy to chemical energy—or may be generated
heterotrophically through the utilization of organic substrates.
Metabolic
Pathways (pp. 164-187)
Respiration
(pp. 165-171)
The
Embden-Meyerhof pathway of glycolysis converts the 6-carbon
molecule glucose into two molecules of the 3-carbon molecule
pyruvate, plus two molecules of reduced coenzyme and two molecules
of ATP.
Glycolysis
is the first step in all pathways of carbohydrate metabolism.
Its product, pyruvate, feeds into
metabolic
PATHWAYS 187
Explosions that Destroy Houses Traced to Methane from Landfill
