III. Keys practical lesson 1 lipids: biological functions and classification. Metabolic pathway of lipids. Digestion and catabolism

1.A.

2.C.

3.C.

4.C.

5.D.

6.E.

7.A.

8.D.

9.A.

10.D. Hormone sensitive lipase is phosphorylated by cyclic AMP-activated protein kinase. Fatty acids released from adipose tissue are carried in the plasma by serum albumin, not VLDL. During a fast, the amount of circulating TG (found in chylomicrons and VLDLs) will be low. Therefore, there is little substrate for LPL. The glycerol produced during TG degradation cannot be metabolized by adipocytes or fibroblasts, but rather must go to the liver where it can be phosphorylated by glycerol kinase.

PRACTICAL LESSON 2

ANABOLISM OF LIPIDS. METABOLISM OF KETONE BODIES

1.E.

2. E.

3. A

4. E.

5. B.

6. D.

7. B.

8. B.

9. E.

10.D.

PRACTICAL LESSON 3

TRANSPORT OF LIPIDS BY BLOOD. METABOLISM OF CHOLESTEROL. PATHOLOGY OF LIPID METABOLISM

1. A

2. D

3.D

4.E

5.A

6.D

7.A

9. D

8.B

10. C

QUESTIONS FOR TEST CONTROL MODULE 5

PRACTICAL LESSON 1

DIGESTION OF PROTEIN. POOL OF AMINO ACIDS.

CONVERSION FOR α- AMINO GROUP

Choose one correct answer

3. Negative nitrogen balance exists in following conditions. Choose one incorrect answer.

6. high level of corticosteroid hormones;

7. after burns;

8. high level of thyroid hormones;

9. fasting;

10. pregnant.

4. Positive nitrogen balance exists in following conditions. Choose one correct answer.

6. the period of active growth;

7. immediately after trauma;

8. prolonged starvation;

9. malignancy;

10. diabetes mellitus.

3. Which one of the following characteristics of peptidases is incorrect?

A. all peptidases are hydrolases;

B. all peptidases are secreted in an active form;

C. all peptidases have substrate specificity;

D. can be endo- and exopeptidases;

E. pancreatic juice contains endo- and exopeptidases.

4. Mechanism of activation proteolytic enzymes is called…

A. allosteric activation

B. isosteric activation;

C. dissociation of protomears;

D. partial proteolysis;

E. covalent modification

5. Intestine juice contains…

A. endopeptidases and exopeptidases;

B. all proteolytic enzymes;

C. aminopeptidases and carboxypeptidases;

D. only dipeptidases and tripeptidases;

E. enzymes secreted in an active form.

6. Pancreatic juice contains…

A. endopeptidases and exopeptidases;

B. all proteolytic enzymes;

C. aminopeptidases and carboxypeptidases;

D. dipeptidases and tripeptidases;

E. enzymes secreted in an active form.

7. End product of putrefaction of tryptophan is…

A. metylmercaptan;

B. putrescin;

C. cadaverin;

D. indole;

E. indican.

8. The organ participating for detoxification toxic products of metabolism is…

A. kidney;

B. heart;

C. brain;

D. liver;

E. lung.

9. There is high level of indole in the urine (indoluria). Give explanation.

A. patient suffers from liver disease;

B. patient suffers from kidney disease;

C. patient suffers from intestine disease;

D. all answers are correct;

E. all answers are incorrect.

10. There is high level of indican in the urine (indicanuria). Give explanation.

A. patient has putrefaction of tryptophan in the intestine, and suffers from liver disease;

B. patient has putrefaction of tryptophan in the intestine, and suffers from kidney disease;

C. patient has putrefaction of tryptophan in the intestine;

D. patient has liver disease;

E. patient has kidney disease.