1. 

2. 

3. 

4. *

5. 

1. Which of the following reactions leads to the formation of acetophenone?

   1. 

   2. 

   3. 

   4. *

   5. 

2. Compound with characteristic smell, which changes coloration of litmus paper, forms gas after the adding of zinc and gives „silver mirror” reaction, is:

   1. НС(О)Н

   2. С6Н5ОН

   3. *НСООН

   4. СН3С(О)Н

   5. СН3СООН

3. At the interaction of carboxylic acids with alcohols at the heating in the presence of H2SO4 form:

   1. Aldehydes

   2. Ethers

   3. Phenols

   4. Ketones

   5. *Esters

4. Potassium stearate – liquid soap, its formula:

   1. C17H33COOK

   2. *C17H35COOK

   3. C17H31COOK

   4. C17H29COOK

   5. C3H7COOК

5. Choose formula of unsaturated carboxylic acid:

   1. *C17H33COOH

   2. C17H35COOH

   3. C3H7COOH

   4. C10H21COOH

   5. C12H23COOH

6. Which of the following carboxylic acids has properties of aldehyde and acid?

   1. CH2Cl – COOH

   2. CH3COOH

   3. *HCOOH

   4. CCl3 – COOH

   5. C3H7COOH

7. Which of the following compounds is a product of propanoic acid chlorination?

   1. CH3 – CH2 – COCl

   2. *CH3 – CHCl – COOH

   3. CH2Cl – CH2 – COOH

   4. CH3 – CH2 – COOCl

   5. C3H7COOH

8. Choose the strongest carboxylic acid:

   1. CH3COOH.

   2. CH3CH2COOH.

   3. CH2Cl – COOH.

   4. *CCl3 – COOH.

   5. CH3CH2CH2COOH

9. In the reaction CH3CH2COOH + NaHCO3 the following gaseous product forms:

   1. CH4

   2. CO

   3. *CO2

   4. C2H6

   5. C2H4

10. Among of the following compounds specify formula of chloroacetic acid:

    1. CH3COOH

    2. *CH2(Сl)COOH

    3. CH2(NH2)COOH

    4. CH2(CH3)COOH

    5. CСl3COOH

11. Determine reaction that cases propanoic acid formation:

    1. CH3-C(O)H + [O] - CH3-COOH

    2. H-C(O)H + [O] - H-COOH

    3. CH3-CH2-CH2-C(O)H + [O] - CH3-CH2-CH2-COOH

    4. *CH3-CH2-C(O)H + [O] - CH3-CH2-COOH

    5. CH3-CH2-CH2-CH2-C(O)H + [O] - CH3-CH2-CH2-CH2-COOH

12. Soap belongs to the following class of compounds:

    1. Alcohols

    2. Carboxylic acids

    3. Esters

    4. *Salts

    5. Phenols

13. Ethyl ester of acetic acid can be obtained by the following reaction:

    1. CH3-CH2-OH + CH3-CH2-OH -

    2. CH3-COOH + CH3-COOH -

    3. *CH3-COOH + CH3-CH2-OH -

    4. CH3 COOH + CH3-OH -

    5. CH3-COOH + Na2CO3

14. Specify compound, which with acetic acid will not form salts:

    1. *CH3-COOH + C2H5OHO

    2. CH3-COOH + Na2CO3

    3. CH3-COOH + Na

    4. CH3-COOH + Mg

    5. CH3-COOH + CH3-COOH

15. Lead (ІІ) acetate has the following formula:

    1. Pb(OH)CH3COO

    2. Pb(CH3COO)4

    3. *Pb(CH3COO)2

    4. Pb(CH3COO)3

    5. Pb(CH3COO)5

16. In the reaction CH3-COOH + NaOH = the following compounds form:

    1. *CH3-COONa + H2O

    2. CH3-COONa + H2

    3. CH3-COONa + O2

    4. 2CH3-COONa + H2O2

    5. 3CH3-COONa + H2O2

17. At the interaction of acetic acid and magnesium (CH3?COOH + Mg) gas … evaporates:

    1. CO2

    2. CO

    3. *H2

    4. H2O(water steam)

    5. С2Н2

18. Ion CH3-COO- has the following name:

    1. Formiate

    2. Carbonate

    3. Hydrocarbonate

    4. *Acetate

    5. Dihydrocarbonate

19. 125. Specify compound, which will not interact with acetic acid:

    1. Nа

    2. NaOH

    3. Na2O

    4. *CO2

    5. Mg

20. Specify compound, which will interact with carboxylic acids:

    1. *NaOH

    2. CO2

    3. H2O

    4. NaCl

    5. KBr

21. Litmus paints solution of acetic acid in ... color:

    1. Green

    2. *Red

    3. Blue

    4. Colorless

    5. Purple

22. For the detection of acetic acid can be used:

    1. *Indicator and sodium hydrogen carbonate

    2. Bromine water

    3. Freshly precipitated Cu(OH)2

    4. Ammonium solution of Ag2O

    5. Lime water

23. In the esterification reaction ОН-group eliminates (for the water formation) from the molecule of:

    1. Alcohol

    2. Ketone

    3. Aldehyde

    4. *Acid

    5. Phenol

24. Method of formic acid obtaining:

    1. Ethane oxidation

    2. *Methane oxidation

    3. Phenol oxidation

    4. Reaction of СН3ОН with СО

    5. Ethylene oxidation

25. For the acetic acid obtaining, as primer compound is used:

    1. HCOON

    2. CH3OH

    3. C4H10

    4. C3H7OH

    5. *С2Н2

26. Glycerin and stearic acid can be obtained by the reaction of:

    1. Etherification

    2. Hydrolysis of carbohydrates

    3. Esterification

    4. *Hydrolysis of fat

    5. Hydratation of carbohydrates

27. Glycerin and palmitic acid can be obtained by the reaction of:

    1. Cracking of petroleum

    2. Esterification

    3. *Hydrolysis of fat

    4. Hydrolysis of carbohydrates

    5. Hydratation of carbohydrates

28. At the hydrolysis of solid fats the following acid forms:

    1. Glycerin

    2. Formic acid

    3. Ethylene glycol

    4. Acetic acid

    5. *Stearic acid

29. Which of the following reaction conducts with hydrogen evaporation?

    1. *СН3 – СООН + Са

    2. СН3 – СООН + NaOH

    3. СН3 – СООН + СаО

    4. СН3 – СООН + СН3OH O

    5. СН3 – СООН + Са(ОН)2

30. Choose the reaction of Carbon (ІV) oxide formation:

    1. СН3 – СООН + NaOH

    2. СН3 – СООН + Zn

    3. *СН3 – СООН + Na2СO3

    4. СН3 – СООН + СаО

    5. СН3 – СООН + Са(ОН)2

31. Which of the following properties are common for methanoic and hydrochloric acid?

    1. Interaction with alkalis and ammonium solution of Ag2O

    2. *Interaction with metals and alkalis

    3. Action of conc. Н2SO4.

    4. Decomposition at the heating

    5. Interaction with fuxin sulfite acid

32. In which of the following rows all compounds will react with formic acid?

    1. СН3С(О)Н; СН3 – ОН; СН3СООН

    2. *С2Н5ОН; Ag2O(ammonium solution); Мg(met.)

    3. Сu(OH)2; Na2CO3; C3H8

    4. CH4; NaOH; CH3Cl

    5. Сu(OH)2; CH4; NaOH; CH3Cl

33. Functional group -COOH has the name:

    1. Aldehyde-group

    2. Hydroxyl group

    3. *Carboxyl group

    4. Keto-group

    5. Phenol hydroxyl

34. Saturated monobasic carboxylic acids have the following general formula:

    1. R-OH

    2. R-C(O)H

    3. R-CH2-OH

    4. *R-COOH

    5. R-C(O)OR

35. Among of the following compounds specify formula of carboxylic acid:

    1. *CH3-COOH

    2. CH3-OH

    3. CH3-CH2-OH

    4. CH3-COH

    5. CH3-C(O)OCH3

36. Methanoic acid has the following formula:

    1. CH3-COOH

    2. CH3-OH

    3. CH3-CH2-OH

    4. *H-COOH

    5. CH3-COH

37. Choose chemical formula of valeric acid:

    1. CH3COOH

    2. CH3CH2COOH

    3. CH3CH2CH2COOH

    4. *CH3CH2CH2CH2COOH

    5. CH3CH2CH2CH2CH2CH2COOH

38. Choose chemical formula of butyric acid:

    1. CH3COOH

    2. CH3CH2COOH

    3. *C3CH2CH2COOH

    4. CH3CH2CH2CH2COOH

    5. CH3CH2CH2CH2CH2CH2COOH

39. The strongest monobasic saturated carboxylic acid is the following one:

    1. *HCOOH

    2. CH3COOH

    3. CH3CH2COOH

    4. CH3CH2CH2COOH

    5. CH3CH2CH2CH2CH2CH2COOH

40. To distinguish formic acid from acetic acid the following reagent can be used:

    1. NH3

    2. NaOH

    3. *[Ag(NH3)2]OH

    4. NaHCO3

    5. Ca(OH)2

41. Salts of methanoic acid are called:

    1. Acetates

    2. Carbonates

    3. Lactates

    4. Propionates

    5. *Formiates

42. Formic acid, except acidic properties, also has properties of:

    1. Alcohols

    2. Ketones

    3. *Aldehydes

    4. Amines

    5. Phenols

43. Product of the formic acid dehydration is:

    1. СО2

    2. *СО

    3. СН4

    4. С2Н2

    5. С2Н4

44. Organic product of the interaction of carboxylic acid with alcohol is:

    1. *Ester

    2. Ether

    3. Ketone

    4. Aldehyde

    5. Anhydride

45. At the total reduction of carboxylic acids are formed:

    1. *Alcohols

    2. Aldehydes

    3. Ketones

    4. Esters

    5. Ethers

46. Choose the formula of ammonium acetate:

    1. NH4Cl

    2. *CH3COONH4

    3. HCOONH4

    4. CH3COON

    5. СН3СН2СООNH4

47. What compound has the biggest acidic properties?

    1. Ethanol

    2. Glycerin

    3. Acetic acid

    4. *Formic acid

    5. Phenol

48. Gaseous product of the “silver mirror” reaction by the participant of methanoic acid is:

    1. CH4

    2. H2

    3. CO

    4. *CO2

    5. С2Н2

49. Gaseous product of the methanoic acid dehydration is:

    1. CH4

    2. H2

    3. *CO

    4. CO2

    5. С2Н2

50. Compound НСООН gives reactions, which are characteristic for:

    1. Organic acids and alcohols

    2. *Organic acids and aldehydes

    3. Alcohols and aldehydes

    4. Aldehydes and esters

    5. Phenols and aldehydes

51. How many asymmetric carbon atoms and possible stereoisomers does tartaric acid have?

1. no asymmetric carbon atoms and it is optically inactive

2. two asymmetric carbon atoms and two stereoisomers

3. *two asymmetric carbon atoms and three stereoisomers

4. two asymmetric carbon atoms and four stereoisomers

5. one asymmetric carbon atom and two stereoisomers

1. How many asymmetric carbon atoms and possible stereoisomers does malic acid have?

1. no asymmetric carbon atoms and it is optically inactive

2. two asymmetric carbon atoms and four stereoisomers

3. *one asymmetric carbon atom and two stereoisomers

4. one asymmetric carbon atom and one stereoisomer

5. two asymmetric carbon atoms and two stereoisomers

1. Which of the following reagent interact with carboxylic-group of

α-bromopropanoic acid?

1. 

2. 

3. 

4. *

5. 

1. How many asymmetric carbon atoms and possible stereoisomers does lactic acid have?

1. no asymmetric carbon atoms and it is optically inactive

2. two asymmetric carbon atoms and four stereoisomers

3. two asymmetric carbon atoms and two stereoisomers

4. *one asymmetric carbon atom and two stereoisomers

5. one asymmetric carbon atom and one stereoisomer

1. Which hydroxyacid does decompose at treatment with conc. H2SO4 according to the following scheme?

1. 

2. 

3. 

4. 

5. *

1. Which hydroxyacid decomposes at treatment with conc. H2SO4 according to the following scheme?

1. 

2. 

3. 

4. 

5. *

1. Which hydroxyacid decomposes at treatment with conc. H2SO4 according to the following scheme?

1. 

2. 

3. 

4. 

5. *

1. What is the product of reaction between pyruvic acid and hydroxylamine?

1. 

2. 

3. 

4. 

5. *

1. What products are formed when diethylacetoacetic ester is treated with diluted

mineral acid?

1. 

2. 

3. 

4. 

5. *

1. What products are formed when methylpropylacetoacetic ester is treated with concentrated solution of alkali?

1. 

2. 

3. 

4. *

5. 

1. What product is formed when γ -hydroxyvaleric acid is heated?

1. 

3. *

4. 

5. 

6. 

1. What product is formed when β -hydroxybutyric acid is heated?

1. 

2. 

3. *

4. 

5. 

1. Choose the correct range of acidity increase for the following compounds.

1. d > b > a > c

2. d < b < a < c

3. c < b < a < d

4. b < a < c < d

5. *c < d < b < a

1. Which is the product of salicylic acid nitration?

1. 

2. 

3. 

4. 

5. *

1. How many asymmetric carbon atoms and possible stereoisomers does α-hydroxybutyric acid have?

1. no asymmetric carbon atoms and it is optically inactive

2. two asymmetric carbon atoms and one stereoisomer

3. one asymmetric carbon atom and one stereoisomer

4. two asymmetric carbon atoms and two stereoisomers

5. *one asymmetric carbon atom and two stereoisomers

1. Malic acid is:

1. monobasic biatomic acid

2. tribasic biatomic acid

3. *dibasic triatomic acid

4. dibasic monoatomic acid

5. tribasic triatomic acid

1. What product is formed when tartaric acid is heated in the presence of KHSO4?

1. 

2. 

3. 

4. *

5. 

1. What product is formed when γ-hydroxybutyric acid is heated?

1. 

2. *

3. 

4. 

5. 

1. What is the identity of the reagent ¬¡ and intermediate B in the following scheme?

1. 

2. *

3. 

4. 

5. 

1. Choose the pair of reagents which can be used to obtain β-hydroxybutyric acid by Reformatsky reaction.

1. 

2. *

3. 

4. 

5. 

1. Choose the correct name of the following compound.

1. oxoketoglutaric acid

2. α-ketopentanedioic acid

3. *β- ketoglutaric acid

4. 2- ketoglutaric acid

5. oxopentanedioic acid

1. Choose the correct name of the following compound.

1. chlorosuccinic acid

2. 3- chlorobutyric acid

3. *3- chlorobutanoic acid

4. α - chloropentanoic acid

5. 3-chloropentanoic acid

1. Which of the following reagent shall react with both functional groups of β-

chloropropanoic acid?

1. 

2. 

3. 

4. 

5. *

1. Citric acid is:

1. monobasic triatomic acid

2. tribasic monoatomic acid

3. *tribasic tetraatomic acid

4. tetrabasic triatomic acid

5. tribasic triatomic acid

1. Trataric acid is:

1. tribasic tetraatomic acid

2. tetrabasic tetraatomic acid

3. tetrabasic biatomic acid

4. *dibasic tetraatomic acid

5. dibasic biatomic acid

1. Which hydroxycarboxylic acid decomposes at treatment with conc. H2SO4

according to the following scheme?

1. 

2. 

3. 

4. 

5. *

1. Which way does citric acid decomposes?

1. 

2. 

3. 

4. 

5. *

1. What product is formed when α-hydroxypropanoic acid is heated?

1. 

2. *

3. 

4. 

5. 

1. What products are formed when acetoacetic ester is treated with concentrated solution of alkali?

1. 

2. 

3. 

4. *

5. 

1. What product is formed when urea is slowly heated?

1. 

2. 

3. *

4. 

5. 

1. What products are formed when ethylacetoacetic ester is treated with diluted

mineral acid?

1. 

2. 

3. 

4. 

5. *

1. Which is the product of the following reaction?

1. *

2. 

3. 

4. 

5. 

1. What products are formed when methylacetoacetic ester is treated with diluted mineral acid?

1. 

2. 

3. 

4. *

5. 

1. Which wayα-chlorosuccinic acid could be obtained?

1. 

2. 

3. 

4. *

5. 

1. Which of the following is α - ketoglutaric acid?

   1. *

   2. 

   3. 

   4. 

   5. 

2. Which of the following compounds is glyoxylic acid?

   1. 

   2. 

   3. 

   4. *

   5. 

3. Which way α-chloropropanoic acid could be obtained?

1. 

2. 

3. 

4. *

5. 

1. Which of the following is tartaric acid?

   1. *

   2. 

   3. 

   4. 

   5. 

2. Which of the following reaction lead to formation of pyruvic acid?

1. 

2. 

3. 

4. 

5. *

1. Which of the following is acetylsalicylic acid?

   1. 

   2. 

   3. 

   4. *

   5. 

2. Which of the following is salicylic acid?

   1. 

   2. 

   3. *

   4. 

   5. 

3. Which of the following is citric acid?

   1. 

   2. 

   3. 

   4. *

   5. 

4. Which of the following is oxalacetic acid?

   1. 

   2. *

   3. 

   4. 

   5. 

5. Which of the following is acetoacetic acid?

   1. 

   2. *

   3. 

   4. 

   5. 

6. Which of the following compounds is o-hydroxycinnamic acid?

   1. *

   2. 

   3. 

   4. 

   5. 

7. Which of the following compounds is malic acid?

   1. 

   2. 

   3. *

   4. 

   5. 

8. Choose the correct name of the following compound.

1. propylbromoacetic acid

2. α - bromovaleric acid

3. 2-bromo-3-methylpropanoic acid

4. *2-bromo-3-methylbutanoic acid

5. α - bromobutyric acid

1. Salicylic acid has two acidic centers and therefore forms two rows of salts. What reagent can be used to form disodium salt of salicylic acid?

   1. *NaOH

   2. NaНCO3

   3. NaCl

   4. Na2SO4

   5. CH3COONa

2. α–Hydroxyacids at the heating will form:

   1. lactides

   2. *lactones

   3. saturated α-acids

   4. esters with open carbon chain

   5. acetoacetic ester

3. Salicylic acid has two acidic centers and therefore forms two rows of salts. What reagent can be used to form disodium salt of salicylic acid?

   1. *NaOH

   2. NaНCO3

   3. NaCl

   4. Na2SO4

   5. CH3COONa

4. Choose acid, which forms -lactone after the heating?

   1. pyruvic

   2. glycolic

   3. lactic

   4. *4-hydroxybutanoic

   5. malic

5. At the adding to the organic compound FeCl3, dark violet color will form. Name this compound?

   1. benzoic acid

   2. benzene

   3. toluene

   4. acetylsalicylic acid

   5. *salicylic acid

6. Galic acid is a part of thiamine. To which class of compounds does this acid belong?

   1. alcohol acids

   2. *phenoloacids

   3. aminoacids

   4. aldehyde acids

   5. ketoacids

7. What compound will form at the interaction of lactic acid with excess of SOCl2?

   1. 2-chloropropanoic acid

   2. chloroanhydride of lactic acid

   3. *chloroanhydride of 2-chloropropanoic acid

   4. 2-chlorolactic acid

   5. 3-chlorolactic acid

8. What reagent is used for the acetoacetic ester determination?

   1. *FeCl3

   2. CuSO4

   3. Formaldehyde

   4. Ethyl alcohol

   5. KMO4

9. Which of the following reagents will react with glyoxylic acid by aldehyde group?

   1. Nа

   2. NaOH

   3. SОCl2

   4. *NH2OH

   5. NaHCO3

10. Which of the following reagents will react with glyoxylic acid by aldehyde group?

    1. Nа

    2. NaHCO3

    3. NaOH

    4. SОCl2

    5. *Ag(NH3)2OH

11. Which of the following reagents will react with glyoxylic acid by aldehyde group?

    1. NaOH

    2. NaHCO3

    3. *HCN

    4. SОCl2

    5. Nа

12. Which of the following reagents will react with glyoxylic acid by aldehyde group?

    1. NaHCO3

    2. *NH2NH2

    3. NaOH

    4. SОCl2

    5. Nа

13. Which of the following reagents will react with glyoxylic acid by aldehyde group?

    1. *NH2NHC6H5

    2. NaHCO3

    3. NaOH

    4. SОCl2

    5. Nа

14. Which of the following reagents will react with glyoxylic acid by aldehyde group?

    1. Nа

    2. NaHCO3

    3. NaOH

    4. SОCl2

    5. *NH2NHC(O)NH2

15. Which of the following reagents will react with glyoxylic acid by aldehyde group?

    1. NaOH

    2. NaHCO3

    3. *NH2NHC(S)NH2

    4. SОCl2

    5. Nа

16. Which of the following reagents will react with glyoxylic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. C6H5NHNH2

    3. NH2OH

    4. *NaHCO3

    5. NH2NH2

17. Which of the following reagents will react with glyoxylic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. *NaOH

    3. NH2OH

    4. C6H5NHNH2

    5. NH2NH2

18. Which of the following reagents will react with glyoxylic acid by carboxylic group?

    1. *Na2CO3

    2. Ag(NH3)2OH

    3. NH2OH

    4. C6H5NHNH2

    5. NH2NH2

19. Which of the following reagents will react with glyoxylic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. NH2NH2

    3. NH2OH

    4. C6H5NHNH2

    5. *Na

20. Which of the following reagents will react with glyoxylic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. C6H5NHNH2

    3. NH2OH

    4. *C2H5OH

    5. NH2NH2

21. Which of the following reagents will react with glyoxylic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. *CH3OH

    3. NH2OH

    4. C6H5NHNH2

    5. NH2NH2

22. Which of the following reagents will react with acetoacetic acid by keto-group?

    1. Nа

    2. NaOH

    3. *NaHSO3

    4. SОCl2

    5. NaHCO3

23. Which of the following reagents will react with acetoacetic acid by keto-group?

    1. NaOH

    2. *NH2OH

    3. SОCl2

    4. Nа

    5. NaHCO3

24. Which of the following reagents will react with acetoacetic acid by keto-group?

    1. Nа

    2. NaHCO3

    3. NaOH

    4. SОCl2

    5. *NH3

25. Which of the following reagents will react with acetoacetic acid by keto-group?

    1. SОCl2

    2. NaHCO3

    3. NaOH

    4. *HCN

    5. Nа

26. Which of the following reagents will react with acetoacetic acid by keto-group?

    1. *NH2NH2

    2. NaHCO3

    3. NaOH

    4. SОCl2

    5. Nа

27. Which of the following reagents will react with acetoacetic acid by keto-group?

    1. NaHCO3

    2. *NH2NHC6H5

    3. NaOH

    4. SОCl2

    5. Nа

28. Which of the following reagents will react with acetoacetic acid by keto-group?

    1. NaOH

    2. NaHCO3

    3. *NH2NHC(O)NH2

    4. SОCl2

    5. Nа

29. Which of the following reagents will react with acetoacetic acid by keto-group?

    1. SОCl2

    2. NaHCO3

    3. NaOH

    4. *NH2NHC(S)NH2

    5. Nа

30. Which of the following reagents will react with acetoacetic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. NH2NH2

    3. NH2OH

    4. C6H5NHNH2

    5. *NaHCO3

31. Which of the following reagents will react with acetoacetic acid by carboxylic group?

    1. *NaOH

    2. Ag(NH3)2OH

    3. NH2OH

    4. C6H5NHNH2

    5. NH2NH2

32. Which of the following reagents will react with acetoacetic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. NH2OH

    3. *Na2CO3

    4. C6H5NHNH2

    5. NH2NH2

33. Which of the following reagents will react with acetoacetic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. *Na

    3. NH2OH

    4. C6H5NHNH2

    5. NH2NH2

34. Which of the following reagents will react with acetoacetic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. NH2NH2

    3. NH2OH

    4. C6H5NHNH2

    5. *C2H5OH

35. Which of the following reagents will react with acetoacetic acid by carboxylic group?

    1. Ag(NH3)2OH

    2. C6H5NHNH2

    3. NH2OH

    4. *CH3OH

    5. NH2NH2

36. γ-Aminobutyric acid takes part in the brain metabolism, is a neuromediator. What substances important for the medicine will γ-aminoacids form at the heating?

    1. *lactames

    2. unsaturated acids

    3. diketopiperazine

    4. lactides

    5. lactones

37. At the heating of α–aminoacids will form:

    1. lactones

    2. lactides

    3. *diketopiperazine

    4. esters

    5. unsaturated aminoacids

38. What compound after the heating does form lactame?

    1. 3-aminobutanoic acid

    2. *4-aminobutanoic acid

    3. 3-hydroxypentanoic acid

    4. 4-amonobenzoic acid

    5. 3-aminopropanoic acid

39. Tyrosine belongs to the aromatic aminoacids. Choose the most correct systematic name foe tyrosine:

    1. *2- amino – 3-(p-hydroxyphenyl) propanoic acid

    2. α- amino-2-hydroxyphenyl propanoic acid

    3. α-amino-4-hydroxyphenyl propanoic acid

    4. 2-amino-3-hydroxyphenyl propanoic acid

    5. 2-amino-3-(m-hydroxyphenyl) propanoic acid

40. Which of the following acids includes asymmetric carbon atom and has optical activity?

    1. (СН3)2-С(ОН)-СООН (α-hydroxyisobutyric acid)

    2. С6Н5СН2СООН (phenylacetic acid)

    3. СН3-С(О)-СООН (pyruvic acid)

    4. *СН3-СН(NН2)-СООН (α-aminopropionic acid)

    5. СН2=СН-СООН (acrylic acid)

41. Choose acid, which forms γ-lactone after the heating?

    1. malic

    2. glycolic

    3. lactic

    4. pyruvic

    5. *4-hydroxybutyric

42. Alanine – aminoacid enters to the protein structure. Choose reagent, which can help to confirm presence of amino-group:

    1. *NaNO2 (HCl)

    2. H2SO4

    3. NaNO3 (HCl)

    4. Ba(OH)2

    5. NaHCO3

43. Choose reagent that is used to protect amino-group of alanine:

    1. CH3–CH2–Cl

    2. CH3OH

    3. *CH3COCl

    4. CH3–NH2

    5. CH3–CHO

44. What reaction is used for deamination of α-aminopropionic acid?

    1. etherification

    2. with formaldehyde

    3. salts formation

    4. *with nitrite acid

    5. acylation

45. Aromatic aminoacids can be detected by the usage of the specific reaction:

    1. biuret reaction

    2. *xantoprotein sample

    3. at the boiling with alkalis with following adding of lead acetate

    4. with Felling reagent

    5. interaction with ninhydrin

46. Point, which of the following w-aminoacids contains imidazole cycle:

    1. alanine

    2. tryptophan

    3. tyrosine

    4. glycine

    5. *histidine

47. What reagent can be used to confirm presence of the primary amino-group in the serotonin molecule?

    1. AgNO3 and NH4OH

    2. *NaNO2 (H+)

    3. Br2

    4. NaHCO3

    5. H2N-NH2

48. Chose reaction of phosgene obtaining:

    1. СО2 + Н2О >

    2. С + Н2 + Cl2 >

    3. *СО + Cl2 >

    4. СО2 + Cl2 >

    5. Cl2 + СН4 >

49. Process 2NH3 + CO2 > cases formation of:

    1. Ether of carbaminic acid

    2. Carbaminic acid

    3. Uretane

    4. Methyl urea

    5. *Urea

50. Which of the following reactions will case formation of methane sulfoacid?

    1. СН4 + SO2 >

    2. *СН4 + SO3 > (at the presence of H2SO4 conc.)

    3. С + Н2 + SO2 >

    4. СO2 + Н2O + SO2 >

    5. СН4 + SO2 > (at the higher pressure)

51. What reaction will case formation of benzene sulfoacid?

    1. *C6H6 + H2SO4 > (oleum)

    2. C6H6 + SO3 >

    3. C6H6 + SO2 >

    4. C6H6 + S + O2 >

    5. C6H6 + SO2 + H2O >

52. 1,3,5-benzene trisulfonic acid forms as a result of double sulfonation of benzene sulfoacid. Choose the mechanism of this reaction.

    1. AN

    2. SN1

    3. SN2

    4. *SE

    5. AE

53. As a result of melting of sulfoacids with alkalis the following compounds form:

    1. Sulfites

    2. Sulfates

    3. Hydrosulfates

    4. *Sulfonates

    5. Carbonates

54. What compound can be obtained by the following reaction? СО + Cl2 >

    1. Urethane

    2. Chlorocarbonic acid

    3. *Phosgene

    4. Carbamide

    5. Carbaminic acid

55. Benzolsulfoacid reduces to:

    1. Sulfur and toluene

    2. Sulfur oxide (VІ)

    3. Benzene and sulfur

    4. Sulfur oxide (ІV)

    5. *Thiophenol

56. For arenesulfoacids the following reactions are characteristic:

    1. AE,AN

    2. *SE,SN

    3. SE,AN

    4. [O]

    5. [H],AE

57. One of the products of arenesulfoacid hydrolysis is:

    1. SO2

    2. S

    3. H2S

    4. *H2SO4

    5. H2SO3

58. Carbonate acid Н2СО3 is unstable. What products will form after its decomposition?

    1. 2СО2 +Н2

    2. НСОН + Н2О

    3. *СО2 + Н2О

    4. СО + Н2О

    5. НСООН + Н2О

59. Carbamide hydrolyses with formation of:

    1. CO2 + 2N2

    2. *CO2 + 2NH3

    3. CO2 + H2O + N2

    4. CO2 + NO + H2

    5. CO + NO2 + H2

60. Few soluble in water urea nitrate forms at the action on carbamide:

    1. *Nitrate acid

    2. Nitrogen oxide (V)

    3. Nitrogen oxide (ІІІ)

    4. Nitrite acid

    5. Potassium nitrate

61. N–acyl derivatives of urea are called:

    1. Carbamides

    2. Urethanes

    3. Anhydrades

    4. *Ureides

    5. Halogenanhydrides

62. As a result of biuret reaction that is used for the detection of urea and proteins will form:

    1. Red color complex

    2. Green color complex

    3. *Red-purple complex

    4. Yellow precipitate

    5. Blue precipitate

63. Barbituric acid is in the base of medical drugs – barbiturates. It belongs to:

    1. Aliphatic ureides

    2. *Cyclic ureides

    3. Uretanes

    4. Anhydrides

    5. Carbamides

64. During the biuret reaction the following side product forms:

    1. *Cyanuric acid

    2. Cyanide acid

    3. Potassium hexacyanoferrate (ІІ)

    4. Potassium hexacyanoferrate (ІІІ)

    5. Potassium cyanide

65. What reaction does case formation of sulfoacid?

    1. Sulfochlorination

    2. Oxidation of thiols

    3. *Oxidation of alcohols

    4. Alkanes sulfonation by oleum

    5. Accession of hydrosulfites to alkenes

66. What reagents will interact with sulfoacids to confirm its acidic properties?

    1. Cu

    2. *NaOH

    3. NO2

    4. HCl

    5. NH3

67. Mixture of o- and p-toluene sulfonic acids will form as a result of sulfonation. Choose the mechanism of this reaction.

    1. AN

    2. SN1

    3. SN2

    4. *SE

    5. AE

68. Sodium benzolsulfonate will form as a result of interaction of:

    1. C6H5SO2OH + Na + O2 >

    2. C6H5SO2OH + Na2O2 >

    3. C6H5SO2OH + Na2O >

    4. C6H5SO2OH + Na >

    5. *C6H5SO2OH + NaOH >

69. Chloroanhydrides of carbonate acids will form as a result of interaction of sulfoacids with:

    1. CHCl3

    2. HClO3

    3. Cl2

    4. *PCl5

    5. HCl

70. Sodium benzolsulfonate is a primary compound for the obtaining:

    1. *Phenols, nitrites

    2. Amides, nitrocompounds

    3. Alcohols, nitrocompounds

    4. Phenols, halogenderivatives

    5. Amides, halogenderivatives

71. Choose the mechanism of benzene sulfonation (formation of benzolsulfoacid):

    1. AN

    2. SN1

    3. SN2

    4. *SE

    5. AE

72. Which reagent can be used in the following reaction?

1. 

2. 

3. 

4. 

5. *

1. Which is the end-product of the reaction of hydrazine with maleic dialdehyde?

1. *

2. 

3. 

4. 

5. 

1. Which is the product of pyridazine reaction with hydrochloric acid excess?

1. 

2. 

3. *

4. 

5. 

1. Select the mechanism of the following reaction and the position of quinoline it will principally occur?

1. 

2. *

3. 

4. 

5. 

1. What is the product of the following reaction?

1. 

2. 

3. *

4. 

5. 

1. What is the product of indigo Blue reduction with glucose solution?

1. indoxyl

2. pyrrole

3. indole

4. *white indigo

5. isatin

1. Choose the correct range of aromaticity decrease for furan, benzene, pyrrole, and thiophene.

   1. 

   2. 

   3. 

   4. 

   5. *

2. What is the product of the following reaction?

1. *

2. 

3. 

4. 

5. 

1. Which of the following compounds are used for pyrrole acetylation?

1. 

2. 

3. 

4. 

5. *

1. The derivatives of which heterocycle are formed as the result of the following reaction (Paale-Knorr synthesis)?

1. 2-aminothiazole

2. indole

3. thiazole

4. *thiophene

5. furane

1. What heterocyclic compound is formed when diammoniac salt tetrahydroxyadipic acid is heated?

1. thiazole

2. aziridne

3. *pyrrole

4. pyrazole

5. azetidine

1. Which of the following heterocycle is the structural fragment of the substance presented below (make the accordance of the substance name with the name of proper heterocyclic moiety)? Haloperidol - neuroleptic:

1. acridine

2. isoquinoline

3. quinoline

4. *piperidine

5. pyridine

1. Which of the following heterocycle is the structural fragment of the substance presented below (make the accordance of the substance name with the name of proper heterocyclic moiety)? Ftivazide (phthivazide) - antimycobacterial drug:

1. acridine

2. isoquinoline

3. quinoline

4. piperidine

5. *pyridine

1. Which of the following heterocycle is the structural fragment of the substance presented below (make the accordance of the substance name with the name of proper heterocyclic moiety)? Cordiamin - CNS stimulant:

1. acridine

2. benzo[n]pyridine

3. piperidine

4. *pyridine

5. benzo[n]pyrone-2

1. Which of the following heterocycle is the structural fragment of the substance presented below (make the accordance of the substance name with the name of proper heterocyclic moiety)? Neocoumarin - anticoagulant:

1. acridine

2. benzo[с]pyridine

3. piperidine

4. pyridine

5. *benzo[в]pyrone-2

1. Which of the following heterocycle is the structural fragment of the substance presented below (make the accordance of the substance name with the name of proper heterocyclic moiety)? Lobelin - alkaloid, analeptic:

1. acridine

2. isoquinoline

3. quinoline

4. *piperidine

5. α-pyrone

1. What is the product of the following reaction?

1. 

2. 

3. *

4. 

5. 

1. Choose the correct range of acidity decrease for the following compounds.

1. 4, 3, 2, 1

2. 1, 3, 2, 4

3. 3, 1, 2, 4

4. *4, 2, 3, 1

5. 1, 2, 3, 4

1. Which type of tautomerism is possible for indoxyl?

1. amino-imine

2. nito-aci-nitro

3. azole

4. *keto-enol

5. lactam-lactim

1. What is the product of pyrrole nitration?

1. 

2. 

3. *

4. 

5. 

1. Choose the product of the following reaction.

1. 

2. 

3. *

4. 

5. 

1. Select the mechanism of the following reaction and the position of coumarin it

will principally occur?

1. 

2. 

3. 

4. *

5. 

1. Select the mechanism of the following reaction and the position of acridine it will principally occur?

1. 

2. 

3. *

4. 

5. 

209. Which is the product of the following reaction?

1. 

2. 

3. 

4. 

5. *

1. Which is the product of the following reaction?

1. 

2. *

3. 

4. 

5. 

1. Which is the product (4) of N-phenylanthranilic acid cyclization?

1. 

2. *

3. 

4. 

5. 

1. Which is the product (2) of the following cyclization?

1. 

2. 

3. *

4. 

5. 

1. Which is the identity of the end-product (№3) in the following scheme?

1. 

2. *

3. 

4. 

5. 

1. Which reaction is Yuriev’s cycle reaction?

   1. 

   2. 

   3. 

   4. *

   5. 

215. Which of the following conpounds can be starting compounds for pyrrole synthesis?

1. acetoacetic ester

2. acetylene

3. diazomethane

4. glyoxal, ammonia, formaldehyde

5. *diammoniac salt tetrahydroxyadipic acid

1. Which of the following reagents can be used for nitration of acidophobic heterocycles?

   1. *

   2. 

   3. 

   4. 

   5. 

2. The derivatives of which heterocycle are formed as the result of the following reaction (Paale-Knorr synthesis)?

1. indole

2. imidazole

3. pyrazole

4. *pyrrole

5. furane

1. The derivatives of which heterocycle are formed as the result of the following reaction (Paale-Knorr synthesis)?

1. pyrrole

2. isooxazole

3. oxazole

4. thiophene

5. *furane

1. At what position of indole will electrophilic substitution reactions principally

occur?

1. position 5

2. position 4

3. *position 3

4. position 2

5. position 1

1. Which is the product of the following reaction?

1. *

2. 

3. 

4. 

5. 

1. Choose the product of the following reaction.

1. 

2. *

3. 

4. 

5. 

1. Choose the product of the following condensation.

1. 

2. *

3. 

4. 

5. 

1. Which of the following compound can be classified as azoles?

   1. antipyrine

   2. pyrrole

   3. azetidine

   4. *thiazole

   5. aziridine

2. Select the mechanism of the following reaction and the position of quinoline it will principally occur?

1. *

2. 

3. 

4. 

5. 

1. Which is the identity of the intermediates (A and B) in the following scheme?

1. 

2. 

3. *

4. 

5. 

1. Which of the following reactions does lead to the barbituric acid formation?

1. 

2. 

3. *

4. 

5. 

1. At what position of pyrimidine will electrophilic substitution reactions (SE) principally occur?

1. *the fifth

2. the fourth

3. the third

4. the second

5. the first

1. Which of the following heterocycle is the structural fragment of the substance presented below (make the accordance of the substance name with the name of proper heterocyclic moiety)? Rivanol - antiseptic :

1. *acridine

2. isoquinoline

3. quinoline

4. piperidine

5. α-pyrone

1. Which reaction characterize the basic properties of purine?

   1. 

   2. 

   3. 

   4. 

   5. *

2. Choose the product of pyrazine oxidation?

1. 

2. *

3. 

4. 

5. 

1. What is the product of pyrazine reduction with sodium in ethanol?