Syphilis

1. A 10-year-old boy presented with Hutchinson’s triad: parenchymatous keratitis, sensorineural deafness and deformed Hutchinson’s teeth (the barrel form), along with saddle-nose deformity.

For what illness the presented changes are characteristic?

A. * Syphilis.

B. Toxoplasmosis

C. Leprosy.

D. Tuberculosis.

E. Opisthorchiasis.

2. An autopsy of a 36-year-old man revealed in his liver s roundish formation, 0,5 cm in diameter. Microscopical investigation showed in the centre of lesion necrotic masses, surrounded by the granulation tissue with some plasmatic and lymphoid cells. There were also signs of the vasculitis in the blood vessels. What is the most likely diagnosis in that case?

A. *Solitary gumma of liver

B. Solitary adenoma of liver.

C. Solitary leproma of liver.

D. Chronic abscess of liver.

E. Carcinoma of liver.

3. An autopsy of a 54-year-old man reveled above valvular rupture of an aorta with resulted in a cardiac tamponade. Histological investigation of ascending part of an aorta showed in its external and middle layers inflammatory infiltrates. They consisted of lymphoid, plasmatic and epithelioid cells. There were also recognized the necrosis centers and proliferation of a vessels’ wall. Changes in an aorta are characteristic for:

A. *Syphilitic aortitis

B. Septic aortitis

C. Rheumatic aortitis

D. Atherosclerosis

E. Hypertension diseases

4. A 20-year old woman presented with enlarged, not painful, condensed inguinal lymph nodes. In her genital mucosa there was a small ulcer with firm edges and the "varnished" grayish color floor. What is the most likely diagnosis?

A. *Syphilis

B. Tuberculosis.

C. Leprosy.

D. Trophic ulcer.

E. Gonorrhea.

5. A biopsy of cervix uteri was taken from the 34-year-old woman. Histological investigation revealed the inflammatory infiltration with involving of fine arteries and veins walls. The infiltrate composed of plasmocytes, lymphocytes, and epithelioid cells. There were also zones of sclerosis and a tissue hyalinosis. What is the most likely disease?

A. * Syphilis

B. Tuberculosis

C. Leukoplakia

D. Cervical erosion

E. Condyloma

6. The prepuce was removed from a young man. A microscopical investigation revealed the polymorphic infiltrate consisting from randomly located plasmatic, lymphoid and epithelioid cells. There was marked vessels’ vasculitis. For what disease the described changes are characteristic?

A. *Syphilis

B. Tuberculosis

C. Actinomycosis

D. Periarteritis nodosa

E. Leprosy

7. A man’s oral cavity investigation revealed an oval, cartilaginous density, slightly elevated ulcer at his buccal mucosa. A meaty, reddened floor was covered with grayish sebaceous deposits. A microscopical investigation showed lymphocyte infiltration, situated mainly round fine vessels. There was also an endothelium proliferation within the vessel’s walls. What disease has developed in that case?

A. * Syphilis

B. Traumatic ulcer

C. Erosive-ulcerated leukoplakia

D. Ulcer-Carcinoma

E. Ulcero-necrotic Vensan's stomatitis

8. A histological study of a biopsy from an oral cavity ulcer revealed the foci of caseous necrosis surrounded with plasmocytes, epithelioid , lymphoid cells and solitary giant multinucleated Pirogov-Langhans’ cells. There were also signs of endo - and a perivasculitis in fine vessels. Specify the disease.

A. *Syphilis

B. Tuberculosis

C. Leprosy

D. Rhinoscleroma

E. Glanders

SEPSIS

1. A 48-year-old patient with a history of croupous pneumonia died of the pulmonary and heart failure. A post-mortem revealed a hyperplasia of a spleen, a thickening and defects of the aortal valve leaflet with large, up to 2 cm in diameter, thrombuses attached to tissues underneath. What is the most likely diagnosis?

A. * Polypous-ulcerative endocarditis

B. Acute warty endocarditis

C. Recurrent warty endocarditis

D. Diffuse endocarditis

E. Fibroplastic endocarditis

2. An autopsy of a 48-year-old man revealed the infarct of the left hemisphere of a brain. A macroscopic study also showed a big septic spleen, immunocomplex glomerulonephritis, ulcers in aortal valve leaflets, covered with polypous thrombi. The latter ones had colonies of staphilococcuses, determined by microscopic study. What disease resulted in cerebral thromboembolism?

A. * Septic bacterial endocarditis

B. Septicemia

C. Acute rheumatic valvulitis

D. Septicopyemia

E. Rheumatic thromboendocarditis

3. A 46-year-old man died of an odontogenic sepsis. An autopsy revealed the marked thickening of semilunar aortic valves. They were whitish, opaque and stiff, with thrombotic masses, 1х1.5 cm in the size on the external surface. What is the most likely form of an endocarditis?

A. * Polypous-ulcerative endocarditis

B. Diffuse endocarditis

C. Acute warty endocarditis

D. Fibroplastic endocarditis

E. Recurrent warty endocarditis

4. A 32-year-old man with a long history of a drug abuse, presented with a fever, the intoxication and a pyuria. An echocardioscopy revealed massive superimpositions (vegetations) on the heart valves. Microbiological blood test showed a presence of a staphylococcus. The patient died of a thromboembolism of a pulmonary artery. Specify the changes of heart, revealed at post-mortem?

A. * Polypous-ulcerative endocarditis

B. Libman-Sacks endocarditis

C. Diffuse valvulitis

D. Acute warty endocarditis

E. Recurrent warty endocarditis

5. A young woman with a history of the out-of-hospital abortion presented with advanced purulent endomyometritis resulted in a lethal outcome. A post-mortem revealed numerous abscesses of lungs, pustules under kidneys’ capsule and spleen hyperplasia. What form of a sepsis has developed?

A. * Septicopyemia

B. Septicemia

C. Chroniosepsis

D. Lung sepsis

E. Urosepsis

6. A 30-year-old woman with a history of abortion presented with purulent endometritis resulted in a death from sepsis. A post-mortem revealed a purulent lymphadenitis, abscesses in lungs, kidneys, a myocardium, a spleen hyperplasia, and dystrophy of parenchymatous organs. Define the clinico-anatomic form of a sepsis.

A. * Septicopyemia

B. Septicemia

C. Septic endocarditis

D. Granulomatous sepsis

E. Chroniosepsis

7. A 28-year-old woman died in the postnatal period. A post-mortem revealed a purulent endometritis and thrombophlebitis of a uterus veins, plural abscesses of lungs, kidneys and a spleen. In addition, there were an apostematous myocarditis and purulent meningitis. What is the most likely kind of a sepsis?

A. * Septicopyemia

B. Septicemia

C. Chroniosepsis

D. The prolonged septic endocarditis

E.

8. A man with a history of a lower extremity wound, presented with persistent pyesis of a lesion, resulted in death of intoxication. An autopsy revealed a cachexia, dehydration; a brown atrophy of a liver, a myocardium, a spleen and cross-striated muscles. In addition, there was amyloidosis of kidneys. What of the listed diagnoses is most probable?

A. * Chroniosepsis

B. Septicopyemia

C. Septicemia.

D. Chernogubov's disease.

E. Brucellosis

9. A post-mortem revealed on the external surface of the aortal valve the large, 1-2 сm, brownish-red, easily crumbling superimpositions (vegetations). They covered ulcerative defects in the valves. What is the most likely diagnosis?

A. * Polypous-ulcerative endocarditis

B. Recurrent warty endocarditis

C. Acute warty endocarditis

D. Fibroplastic endocarditis

E. Diffuse endocarditis

10. A man with a wound of his limb that had been suppurating for a long time died from intioxication. Autopsy revealed extreme emaciation, dehydration, brown atrophy of liver, myocardium, spleen and cross-striated muscles as well as renal amyloidosis. What diagnosis corresponds with the described picture?

A. *Chroniosepsis

B. Brucellosis

C. Chernogubov's syndrome

D. Septicopyemia

E. Septicemia

11. A 20 year old patient died from intoxication 8 days after artificial illegal abortion performed in her 14-15th week of pregnancy. Autopsy of the corpse revealed yellowish colour of eye sclera and of skin, necrotic suppurative endometritis, multiple pulmonary abscesses, spleen hyperplasia with a big number of neutrophils in its sinuses. What complication after abortion was developed?

A. *Septicopyemia

B. Hemorrhagic shock

C. Chroniosepsis

D. Septicemia

E. Viral hepatitis type A