64. What microorganism is a common reason of bacterial meningitis in newborns?
А. Streptococcus agalactiae.
В. Streptococcus pneumoniae.
C. Staphylococcus aureus.
D. Klebsiella pneumoniae.
Е. Escherichia coli.
65. Virological and bacteriological method of the researched material revealed the agents of measles and scarlet fever. What kind of infection is it?
А. Mixed.
В. Long-lasting.
С. Latent.
D. Chronic.
Е. Inapparent.
66. A boy of 12 years old developed rheumatic endocarditis after the attack of quinsy. Every next streptococcal infection worsens the condition of the patient. What preparation is relatively safe for the prophylaxis of complications?
А. Streptococcal toxoid.
В. Bensolpenicillinum sodium salt.
С. Streptococcal bacteriophage.
D. Donor γ (gamma) - globulin.
Е. Autovaccine.
67. A 2-year-old child was introduced with a small amount of serum against erythrogenous toxin of streptococcus subcutaneously. Skin rash disappeared on the place of injection. What is the result of reaction evident of?
А. The whole serum dose can be introduced intravenously.
В. The child is hypersensitive to erythrogenous toxin.
С. The disease was caused by nonhemolytic streptococcus.
D. Clinical diagnosis is confirmed.
Е. Immune system of the child is weakened.
68. A patient is diagnosed with "croupous pneumonia". Microscopy of the pus from the sputum revealed Gram-positive diplococci of lancetical form with a capsule. What agent caused the disease?
А. Streptococcus pneumoniae.
В. Klebsiella pneumoniae.
С. Chlamуdia pneumoniae.
D. Staphylococcus aureus.
Е. Escherichia coli.
69. Infection of gall bladder was caused by microorganisms similar to pneumococci. Due to biological properties bacteriologist related them to streptococci of group D. What microorganisms are most likely to cause the disease?
А. Faecal enterococci.
В. Streptococci with a green zone of haemolysis.
С. Pyogenic streptococci.
D. Lancetical diplococci.
Е. Haemolytic streptococci.
70. An attack of flu was followed by pneumonia and the patient was hospitalized to the infectious department. Investigation of the sputum revealed Gram-positive cocci. The growth of bacteria on nutrient medium was characterized by the development of β-hemolysis. What nutrient medium was used for investigation?
А. Blood agar.
В. Yolk-salt agar.
С. Kitt-Tarozzi medium.
D. Endo agar.
Е. Serum agar.
71. A 7-year-old patient presented to the hospital with hyperemia of the skin, bright red small spots on the forehead, neck, groins, and popliteal area; nasolabial triangle seemed pale. There were observed local bright red hyperemia in the throat, swollen tonsils, pus in the lacunes and "strawberry tongue". Cervical lymphatic nodules were enlarged, dense and painful on palpation. What disease was the patient diagnosed with?
A. Infectious mononucleosis.
B. Rubella.
C. Diphtheria.
D. Pertussis.
E. Scarlet fever.
G
ram-negative
Cocci:
Neisseria
(Coffee-bean Shaped Diplococci)3
72. Which of these microorganisms can cause specific inflammation?
А. Gonococcus.
B. Volkouvich-Frisch bacilli (Klebsiella pneumoniae, subsp. rhinoscleromatis).
C. Staphylococcus.
D. Streptococcus.
Е. Leoffler’s bacillus.
A patient is diagnosed with gonorrhea. What is bacteriological investigation performed for?
А Identification of antibiotic sensibility.
В. Identification of biochemical properties of culture.
С. Determination of phagotype.
D. Making a diagnosis more precise.
Е. Determination of pathogenic properties of the microorganism.
74. A patient is hospitalized with the suspicion of chronic gonorrhea. What serological two-phased reaction must be carried out for determining specific antibodies in the patient’s serum?
А. Complement fixation test (Bordet-Gengou test).
В. Reaction of neutralization.
С. Agglutination test.
D. RIA (Radioimmune assay).
Е. ELISA (enzyme-linked immunosorbent assay).
75. A child is hospitalized with the symptoms of headache, vomiting and slurred speech. Lumbar puncture was made and Gram-negative diplococci located mainly intracellularly were revealed. What is the cause of this case?
А. Neisseria meningitides.
В. Staphylococcus aureus.
С. Influenza virus.
D. HIV.
Е. Poliovirus.
Pure culture of coccus was isolated from the urethral discharge of a patient with urethretis. This isolated microorganism ferments glucose only into acid. What microorganism is it?
А. Neisseria gonorrhoeae.
В. Neisseria meningitidіs.
C. Staphylococcus aureus.
D. Streptococcus pyogenes.
Е. Enterococcus faecalis.
77. Pure culture of polymorph coccus capable to ferment glucose and maltose into acid was isolated from the material of a
5-year-old child. What microorganism is it?
А. Meningococcus.
В. Staphylococcus.
C. Streptococcus.
D. Pneumococcus.
Е. Gonococcus.
78. A group of people who had been in contact were tested for chronic type of gonorrhea. They were administered serological research of blood serum with complement fixation test and skin allergic test with gonococcal allergen. Why were those two methods used?
А. They allow choosing patients for more accurate research.
В. They are the most informative for the confirmation of diagnosis.
C. They allow making proper diagnosis in short terms.
D. They can be performed in any hospital.
Е. This is doctor’s wish.
79. A patient is tested for toxoplasmosis and chronic form of gonorrhea according to the rules of sterility. What reaction must be performed for the confirmation of the above mentioned diseases?
А. Complement fixation test.
В. IFT.
C. Immunoblotting.
D. PIHAT (passive indirect hemagglutination test).
Е. Counter electrophoresis.
80. Bacteriologist prepared a pus smear from the patient’s urethra by Gram staining. Microscopy revealed a great number of leucocytes, in the cytoplasm of which there were a lot of Gram-negative dyplococci in a shape of coffee beans. What is the result of this process?
А. Phagocytosis.
В. Metabolism.
C. Formation of capsule.
D. Formation of spore.
Е. Malignation.
81. A 5-year-old patient complains of bad headache and vomiting. Objectively: rigidity of the occipital muscles, occasional vomiting, nausea, herpes on the face, and fever. What material can prove the preliminary diagnosis of cerebrospinal meningitis?
А. Puncture of cerebrospinal fluid which runs out under pressure with unpleasant odor.
В. Identification of N. meningitidis in urine culture.
C. Identification of N. meningitidis in stool culture.
D. Research of vomiting mass.
Е. Identification of N. meningitidis on the mucous membrane of urogenital system.
82. During bacteriological investigation of pyogenic discharge from urethra there were discovered Gram-negative coffee-bean shaped bacteria which could ferment glucose into acid and were settled inside cytoplasm of leucocytes. What disease can these microorganisms cause?
А. Gonorrhea.
В. Syphilis.
C. Veneral lymphogranulomatosis.
D. Soft chancre.
Е. Meloidosis.
83. Light blue colonies grew on special enriched media after having been inoculated from the urethra. Microscopy revealed Gram-negative coffee bean shaped diplococci. What disease can these microorganisms cause?
А. Chlamydiosis.
В. Gonorrhea.
C. Syphilis.
D. Tularaemia.
Е. Meliodosis.
84. Smear was taken from a patient suspected of chronic form of gonorrhoea. Three days earlier the patient had treated himself with penicillin. L-forms of gonococcus are observed under the microscope. What is the effect of penicillin on gonococcus?
А. It destroys protein synthesis.
В. It destroys cell wall synthesis.
C. It destroys aminoacid synthesis.
D. It changes penetrative function of cytoplasm membrane.
Е. It destroys adhesion.
85. The staff and children of a kindergarten are to be tested for meningococcal infection. Choose the method of microbiological research.
А. Skin allergic test.
В. Bacteriological.
C. Bacterioscopical.
D. Biological.
Е. Serological.
86. Gram - negative coffee bean shaped diplococci were found in the pyogenic discharge from the neck of uterus. They were located in leucocytes and outside them. They created a film in a fluid medium; they were inactive biochemically, produced endotoxin and could stimulate the inflammation of uterus. What agent caused the inflammation of the uterine neck?
А. Chlamydia trachomatis.
В. Haemophilus vaginalis.
C. Trichomonas vaginalis.
D. Neisseria gonorrhoeae.
Е. Calymmatobacterium granulomatis.
87. Bacteriologist followed all the rules during the research of a pathological material (cerebrospinal fluid, mucus from the pharynx, blood) because of high sensibility to environmental factors (low temperature) and to the demands of the celective media. Microscopy revealed Gram-negative coffee bean shaped cocci arranged in pairs or in tetrads. Name the isolated causative agent.
А. Neisseria meningitidis.
В. Staphylococcus aureus.
C. Neisseria gonorrhoeae.
D. Moraxella lacunata.
Е. Acinetobacter calcoaceticus.
88. During bacteriological investigation of the material taken from the patient suspected of chronic gonorrhoea no growth of microorganisms on special enriched media was observed. What method of diagnostics is to be used to confirm or deny the diagnosis of chronic gonorrhea?
А. Complement fixation test, skin allergic test with gonococcal antigen.
В. Determination of antibodies titre in patient’s blood serum using passive haemagglutination test.
C. Biological method.
D. Immune electrone microscopy.
Е. Reinvestigation of the material in differential-diagnostic medium.
89. Cerebrospinal fluid of a child suffering from cerebrospinal meningitis contained a great number of leucocytes. What serological reaction should be performed for express diagnostics of the disease?
А. Agglutination test.
В. Precipitation test.
C. Complement fixation test.
D. HAT (haemagglutination test).
Е. Neutralization test.
90. A child is suspected of pyogenic keratoconjuctivitis of ophthalmia neonatorum (gonococcal conjunctivitis, blennorrhea). What methods are most likely to confirm the diagnosis?
А. Microscopic and bacteriological.
В. Serological and skin allergic tests.
C. Biological and methods of bacteriophage typing.
D. Biological and skin allergic tests.
Е. Microscopic and serological.
91. A child suffering from nasal pharyngitis is diagnosed with meningococcal infectious disease. Which method of diagnostics is the most effective for the confirmation of diagnosis?
А. Biological test.
В. Serological.
C. Microscopic.
D. Bacteriological.
Е. Skin allergic test.
92. A patient is suspected of acute form of gonorrhea. Gram staining of the pus obtained from the urethra of the patient revealed a great number of cocci. What tinctorial properties and the way microorganisms are arranged in the preparation confirm this diagnosis?
А. Gram-positive cocci located in leucocytes and outside them.
В. Gram-positive diplococci located in leucocytes and outside them.
C. Gram-positive tetracocci located in leucocytes and outside them.
D. Gram-positive cocci arranged in chains.
Е. Gram-negative coffee-bean shaped diplococci located in leucocytes and outside them.
93. A patient who is known to have suffered from gonorrhea but recovered completely is diagnosed with acute gonorrhea again. What type of the disease is it?
А. Recurrence.
В. Secondary infection.
C. Reinfection.
D. Autoinfection.
Е. Superinfection.
94. There are some pathological processes associated with microbic factors: meningococcemia, acute pyelonephritis caused by Klebsiella, septic condition caused by Escherichia coli, bad wound infection caused by Proteus vulgaris and endometritis caused by enteroinfection of unknown origin. Name the common sign of these diseases.
А. Bacterial protein toxin intoxication.
В. Sepsis.
C. Intoxication caused by lypopolysaccharide endotoxin.
D. Presence of Gram-negative bacteria in blood.
Е. Septicemia with the development of allergic reactions.
95. Choose the condition which can ensure the right results in investigation of meningococcal infection:
А. Transportation of the material in cool condition
(t = 0-4,5 °C).
В. Transportation of the material in elective medium
(t = 37,5 °C, 1 hour).
C. Transportation of the material in preserving medium
(t = 20,5 °C).
D. Growth of the material obtained near the bed of the patient into MPB with protein.
Е. Transportation of the material in selective medium
(t = 37,5 °C, 1 hour).
96. Gram-negative diplococci located inside and outside leucocytes were identified in the preparation made from the patient’s cerebrospinal fluid which ran out under pressure during lumbar puncture. What is this disease called?
А. Blue pus bacillus.
В. Meningococcal infection.
C. Staphylococcal infection.
D. Tuberculosis.
Е. Pneumococcal infection.
97. A 5-year-old child presented with elevated body temperature up to 40 °C, headache, vomiting, anxiety, and chills. 4 days later hemorrhagic rash on the skin, olyguria, and suprarenal failure developed and it led to death. Meningococcus was determined during bacteriological research of pharyngeal smears. What type of disease was observed?
А. Meningococcemia.
В. Hydrocephaly.
C. Meningoencephalitis.
D. Meningococcal nasopharyngitis.
Е. Meningococcal meningitis.
98. Mother of a neonate visited an ophthalmologist of the outpatient department complaining of pyogenic discharge from the conjunctiva of the child’s eye. A great number of leucocytes and Gram-negative bean-shaped dyplococci were revealed inside leucocytes. What is the causative agent of the disease?
А. Streptococcus pyogenes.
В. Neisseria catarrhalis.
C. Staphylococcus epidermidis.
D. Neisseria gonorrhoeae.
Е. Staphylococcus aureus.