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23. Heart. Biophysical property of heart.

The heart is located in the chest between the lungs behind the sternum and above the diaphragm. It is surrounded by the pericardium. Its size is about that of a fist, and its weight is about 250-300 g. Its center is located about 1.5 cm to the left of the midsagittal plane. Located above the heart are the great vessels: the superior and inferior vena cava, the pulmonary artery and vein, as well as the aorta. The aortic arch lies behind the heart. The esophagus and the spine lie further behind the heart.

In the heart muscle cell, or myocyte, electric activation takes place by means of the same mechanism as in the nerve cell - that is, from the inflow of sodium ions across the cell membrane. The amplitude of the action potential is also similar, being about 100 mV for both nerve and muscle. The duration of the cardiac muscle impulse is, however, two orders of magnitude longer than that in either nerve cell or skeletal muscle. A plateau phase follows cardiac depolarization, and thereafter repolarization takes place. As in the nerve cell, repolarization is a consequence of the outflow of potassium ions. The duration of the action impulse is about 300 ms.

Associated with the electric activation of cardiac muscle cell is its mechanical contraction, which occurs a little later.

Located in the right atrium at the superior vena cava is the sinus node (sinoatrial or SA node) which consists of specialized muscle cells. The sinoatrial node in humans is in the shape of a crescent and is about 15 mm long and 5 mm wide. The SA nodal cells are self-excitatory, pacemaker cells. They generate an action potential at the rate of about 70 per minute.

The atrioventricular node (AV node) is located at the boundary between the atria and ventricles; it has an intrinsic frequency of about 50 pulses/min.

The cardiac muscle possesses the next properties: excitability, ability to spend excitation and contractility.

Conductivity. Waves of excitation are spent on fibers of a cardiac muscle and a so-called special tissue of heart with unequal speed.

Contractility: Physiological features of a cardiac muscle is extended refractory period and automatism.

24. Rhythm of heart. Parameters of cardiac activity.Heart tones.

Rhythm of heart is the quantity of reductions in 1 minute, depends mainly on a functional condition of wandering and sympathetic nerves. At excitation of sympathetic nerves frequency of cardiac reductions increases, this is called atachycardia. Frequency of cardiac reductions decreases at excitation of wandering nerves,is is called a bradycardia.

Parameters of cardiac activity. Parameters of work of heart are systolic and minute volume of heart. Systolic or shock volume is the quantity of blood, which heart throws out in corresponding vessels at each reduction. The minute volume of heart is a quantity of blood, which heart throws out in a pulmonary trunk and an aorta for 1 minutes.

Cardiac tones are the sound phenomena arising in working heart. It is possible to distinguish two tones: I-systolic and II - diastolic.Systolic tone. During a systole ventricles atrioventricular valves are closed, and fluctuations of their shutters and attached to them tendinous strings cause I tone. On sound features I tone is lingering and low. Diastolic tone arises in the beginning diastole of ventricle during protodiastolic phase, when there is a closing of semilunar valves. II tone is short and high.

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