- •Contents:
- •Introduction
- •Structure, functions and methods of research of biological membranes The general structure of cell
- •Ultrastrucrure and function of function of biological membrane
- •Kinds of passive transport
- •Methods of research of structure and functions of biological membranes
- •Method of a dark field.
- •Phase - contrast method.
- •Electronic microscopy.
- •Method of diffraction of X-rays radiation.
- •Ultramicroscopy.
- •Luminescent methods of research of membranes.
- •Method of ultrachemistry.
- •Nuclear magnetic resonance research and electronic paramagnetic resonance research.
- •Research of forces of a superficial tension Properties of liquids
- •Superficial tension.
- •Physical properties of biological membranes.
- •Molecular mechanisms of electrochemical potentials of membranes and distribution of a nervous impulse along excitability fibre.
- •Principles of transformation of biological and not electric signals in electric. Designs of sensors and electrodes, their basic characteristics
- •Application of sensors
- •Analog registering devices
- •Rhythm of heart. Parameters of cardiac activity.
- •External displays of activity of heart.
- •Activity of heart
- •Electric activity of cells of a myocardium
- •Functions of conductive system of heart
- •The electrocardiogram
- •Change of a rhythm of cardiac activity.
- •The device and main principles of work of electrocardiograph
- •Imposing of electrodes
- •The device, a principle of work of electroencephalograph. Basic rhythms of eeg. Registration of eeg and principles of the analysis
- •Introduction
- •Essence of a method
- •Technique of record of electroencephalogram.
- •Principles of analyses of electroencephalogram
- •Definition of a photoeffect
- •Types of photoeffects.
- •Einstein equation
- •Application of a photo effect in medicine.
- •The device, principle of work spectrophotometer. Application spectrophometrical methods of research for definition of concentration of substances in biological liquids
- •Method of the calibre graph.
- •Method of comparison.
- •Polarization of light by biosystems. Polarimeter. Light natural and polarized. Polaroids.
- •Research of microstructures in polarizing light
- •Rotation of a plane of fluctuations of polarized light. Saccharimetry.
- •Design of the device
- •Principle of action
- •Special receptions of microscopy of biological objects Special methods of light microscopy (illumination and supervision). Method of a dark field.
- •Method of ultramicroscopy
- •Method of a light field and its version
- •Method of phase contrast
- •Polarizing microscopy
- •The method interference contrast
- •Method of research in a view of a luminescence
- •Device of a microscope. Measurement of value of microscoping object.
- •Model of sliding strings. Biomechanics of a muscle. The equation of Hill. Modeling of muscular reduction Biophysics of muscular reduction
- •Structure of a cross-section-striped muscle. Model of sliding strands.
- •Biomechanics of a muscle
- •The equation of Hill. Power of single reduction.
- •Modelling of muscular reduction
- •Electromechanical interface in muscles
- •Devices for measurement of function of external breath. The device and a principle of work. Registration and the analysis of the given functional researches
- •Change of saturation by gases of an organism at differences of external pressure.
- •Biomechanics of external breath
- •Devices for measurement of function of external breath
- •Viscosity of a liquid
- •Current of a liquid on a horizontal pipe. Puazal’s law.
- •Current of a liquid on a pipe of variable section and branched out
- •Definition of speed of blood-groove
- •Full resistance (impedance) of tissues of the organism Physical bases of rheography
- •Measurement of factor of viscosity.
- •Physical bases of hemodynamic. Laws of movement of blood in an arterial and venous channel
- •Measurement of pressure of blood
- •Systolic and minute volume of a blood-groove
- •Change of minute volume of a blood-groove at work.
- •Biophysical features of an aorta.
- •Biophysical features of arterioles of the big circle of blood circulation.
- •Tomographic methods
- •Classification of kinds of a tomography.
- •Interposition of a source of probing radiation, bject and the detector.
- •Echosounding
- •Computer tomograph.
- •Magnetic-resonant tomography.
- •Three-dimensional ultrasonic
- •ElastoScan-flexography
- •Modes of an acoustic transparency of three-dimensional ultrasonic.
- •Methods of physiotherapeutic influence
- •The therapeutic techniques based on application of a direct current. Electrophoresis and galvanizing in a medical practice. Mobility of ions.
- •Medicinal electrophoresis.
- •Galvanizing.
- •Electrosecurity
- •The basic requirements to an electrosecurity of electromedical devices and devices.
- •Modelling of biophysical processes.
- •The basic stages of modelling
- •The basic stages of modelling
- •4. Creation of model, its research.
- •Classification of models:
- •Mathematical models of growth of number of a population.
- •Pharmacokinetic model.
- •Sources of X-ray radiation.
- •Artificial sources of radiation.
- •Interaction of X-ray radiation with substance.
- •1. Coherent dispersion;
- •2. Photoeffect
- •3. Kompton - effect
- •Radioactivity radiation Radioactive disintegration Structure of a nucleus
- •A radioactive disintegration. Kinds of radioactive radiation
- •It is thrown out and a nucleus has more stability complex of nucleons. Positron β-disintegration is described by the equation:
- •The basic law of radioactive disintegration in the differential form. A constant of disintegration.
- •The basic law of radioactive disintegration in the differential form.
- •A half-life period.
- •Activity. A unit of measure.
- •Radioactive elements in the nature.
- •Ionizing radioactive radiation and its biological action.
- •The absorbed and exposition doze. Power of a doze. Units of measure.
- •Relative biological efficiency.
- •Mehanisms of action of laser radiation on biological tissues.
- •Mechanisms of action of laser radiation on biological tissues
- •Список использованной литературы :
- •Educational handout on medical biophysics kovaleva larissa valentinovna
Application of a photo effect in medicine.
Electrovacuum or semi-conductor devices, which principle of work it is based on a photo effect, name photoelectronic. We shall consider an arrangement of some of them.
The most widespread photoelectronic device is the photo cell.
The photo cell based on an external photo effect, will consist of a source of electrons — the photocathode K on which light gets, and anode A. All system is concluded in a glass cylinder from which air is pumped out.
The photocathode is a
photosensitive layer, it may be directly put on a part of inner
surface of a cylinder. In picture the diagram of inclusion of the
photocathode in a circuit is given.
Basic parameter of a photo cell — its sensitivity expressed by the attitude of force of a photocurrent to appropriating light stream.
To an increase of force of a photocurrent apply
Fig.1. also photo cells in which there is a dependent dark category in inert gas, and secondary electronic issue — the emission of electrons which is resulting from bombardment of a surface of metal by a bunch of primary electrons. The last finds application in photoelectronic multipliers (FEM).
Scheme of FEM is shown in fig. 3. Falling on the photocathode K photons lets out electrons which are focused on the first electrode Э1.
As a result of secondary electronic issue from it electrode takes off more electrons, than falls on it. There is as though a multiplication of electrons.
Fig. 2.
Being multiplied by the following electrodes, electrons as a result form time strengthened in hundred thousand a current in comparison with a primary photocurrent.
FEM apply mainly to measurement of small radiant streams, in particular them register a superweak bioluminescence that is important at some biophysical researches.
Work of the electron-optical converter is based on an external photoeffect (EOC) , the image intended for transformation from one area of a spectrum in another, as well as for strengthening brightness of images.
T
he
diagram of the elementary electronic-optical converters (EOC) is
resulted on fig. 4. The light image of object 1 projected on the
translucent photocathode K, it will be transformed in the electronic
image 2. Accelerated and focused electric Fig.
3.
field of electrodes Э
electrons get on luminescent screen E.
In medicine EOC are applied for strengthening of brightness of the
x-rayed image, it allows considerably to decrease the dose of
irradiation of man.
If signal from EOC to give as an involute on the televisional system, then on the TV screen it is possible to get " the thermal" image of objects. Parts bodies having different temperatures differentiate on the screen either a color at the coloured image or light, if image black-white. Such technical system is called thermal image, is used in a thermography.
В
ентильные
photo cells offer advantage before vacuum as work without a source of
a current. One of such photo cells — copper-oxide — is presented
on the diagram fig. 5.
The copper plate serving one electrodes,
Fig.
4.
becomes covered by a thin layer of
protoxide copper Сu2SО
(semiconductor). On protoxide the transparent layer of metal (for
example, gold Аu)
which serves the second electrode is put to copper.
I
f
a photo cell to shine through the second electrode between electrodes
there will be a photo-electromotive force, and at short circuit of
electrodes, in an electric circuit the current depending on a light
stream will go.
Sensitivity gated photo cells reaches several thousand microampere on a lumen. On the basis of highly effective gated photo cells with efficiency, equal 15 % for a sunlight, create special solar batteries for a feed of the onboard equipment of satellites and spacecrafts. Dependence of force of a photocurrent on light exposure (light stream) allows the use of photo cells as luxmeter, that finds application in a sanitary-and-hygienic practice and at photographing for definition of an exposition (in exposure meter).
The some people gated photo cells (sulphureous-thallic, germanium, etc.) are infrared-sensitive, them apply to tracking down heated invisible bodies, as though expand possibilities of vision.
Other photo cells (selenic) have the spectral sensitivity close to a human eye, it opens possibilities of their use in automatic systems and devices instead of an eye as objective receivers of a visible range of light.
The phenomenon of the photoresistor is based on the phenomenon of photoconductivity also. The elementary photoresistance (fig. 6) represents a thin layer of the semiconductor 1 with metal electrodes 2; 3 — an insulator. Photoresistance, as well as photo cells, allow to define some light characteristics and are used in automatic systems and the measuring equipment.
Thus, a photoeffect is the phenomenon connected with deliverance of electrons of a firm body (or liquids) under action of electromagnetic radiation.
Distinguish:
1) an external photoeffect – emission of electrons under action of light (photoelectronic issue),
radiations, etc.;
2) an internal photoeffect – an increase электропроводности semiconductors or dielectric under action of light (photoconductivity);
3) gated a photoeffect – excitation by light of electromotive power on border between metal and the semiconductor or between diverse semiconductors.
Photoionization of gases sometimes also is named a photoeffect.
