Indications for use:

∙ mental retardation, cerebral palsy, mental retardation and / or psychomotor development,

prevention of cerebral disorders in newborns from high-risk groups;

∙ atherosclerosis of cerebral vessels, discirculatory and hypertensive encephalopathy,

cerebral stroke and its consequences;

∙ mnestic disorders in alcoholism, epilepsy, neuroinfections;

∙ post-traumatic acute and chronic brain damage;

∙ asthenia and depression in the elderly, senile depression;

∙ neurotic conditions, severe stress with overwork, impaired mental and social adaptation;

∙ dizziness;

∙ coma of vascular, toxic or traumatic etiology;

∙ correction of tics in patients with Tourette's syndrome and attenuation of attention deficit hyperactivity disorder (GUANFACIN in small doses);

∙ Parkinson's disease, moderate cognitive impairment, including those associated with age-related cognitive dysfunction and dyscirculatory encephalopathy, age-related sensorineural hearing loss, restless legs syndrome (PIRIBEDIL);

∙ prevention of motion sickness in children (FENIBUT, AMINALON);

∙ stuttering, tics, enuresis in children (FENEBUT);

∙ Parkinson's disease (PIRIBEDIL).

Side effects:

∙ allergic reactions;

∙ headache, dizziness, weakness;

∙ dyspeptic disorders;

∙ irritability, anxiety, anxiety, insomnia, anxiety, (except for GUANFACIN, Phenibut, Cinnarizin, FESAM);

∙ PIRIBEDIL: orthostatic hypotension, flatulence, hallucinations (in predisposed persons);

∙ GUANFACIN: dry mouth, drowsiness, impotence, depression; sudden withdrawal of the drug can cause a hypertensive crisis;

∙ AMINALON: feeling of heat, fluctuations in blood pressure;

∙ PHENIBUT: drowsiness;

∙ GINKGO BILOBA LEAVE EXTRACT: stomatitis;

∙ PIRACETS: exacerbation of angina pectoris in the elderly, weight loss, aggressive behavior, fluctuations in blood pressure;

∙ PYRIDITOL: rarely - alopecia, arthralgia, thrombocytopenia, agranulocytosis, muscle weakness, paresthesia, taste disturbance, anorexia, diarrhea;

∙ ACEFEN: increased delirium, hallucinations, anxiety in mental patients, provocation of arrhythmias (ACEFEN is cleaved to form n-chlorophenoxyacetic acid and dimethylamineethanol, which acts as a choline antagonist in the synthesis of acetylcholine);

∙ CEREBROLYSIN: fever, hot flashes, confusion, hallucinations (in patients with dementia);

∙ CINNARIZIN: drowsiness, dry mouth, increased sweating, arterial hypotension, redness of the face and skin of the upper body, edema of the lower extremities; the appearance (aggravation) of extrapyramidal disorders in certain elderly patients;

∙ NICERGOLIN: discomfort in the heart or abdomen, orthostatic hypotension, impaired ejaculation, sweating;

∙ KAVINTON, VINKAMIN: arterial hypotension, tachycardia, extrasystole, thrombophlebitis at the injection site, heartburn, dry mouth, skin flushing.

∙ PANTOGAM: ∙ a syndrome similar to Reye's syndrome (encephalopathy and fatty degeneration of internal organs), due to impaired metabolism of carnitine;

∙ FESAM: dry mouth, weight gain, drowsiness, extrapyramidal disorders.

Contraindications

∙ persistent and significant disorders of mental activity and intelligence;

∙ PIRACETS: acute renal failure, diabetes mellitus (granules), childhood (up to 1 year);

∙ PHENIBUT and PANTOGAM: pregnancy and breastfeeding;

∙ PANTOGAM and PICAMILON: acute and chronic kidney disease;

∙ PYRIDITOL and ACEPHENE: mental agitation, epilepsy, increased convulsive readiness, neuroinfections, myasthenia gravis.

Comparative evaluation:they do not have a pronounced psychostimulating or sedative effect. At the same time, they stimulate the transfer of information between the cerebral hemispheres, improve energy and plastic processes in the brain tissue. All nootropic drugs are characterized by low toxicity and good tolerance by patients of different age groups.