Заключение

Несмотря на десятилетия интенсивных исследований, основные аспекты функционирования сигнальной системы ИФР по-прежнему остаются плохо понятными. Главным среди них является роль ИФР-П в физиологии человека. Кроме того, абсолютно не изучено совместное действие ИФР-1 и ИФР-И на клеточном уровне, несмотря на то что большинство тканей в организме человека обычно подвергается комбинации эндокринного, паракринного и часто аутокрипного действия обоих факторов роста. В контексте данной книги комплексность системы ИФР предоставляет широкий спектр мишеней, через которые могут быть опосредованы эффекты воздействия физических упражнений па физиологические и патофизиологические процессы, в регуляции которых принимает участие ИФР.

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